TOP 10 Hotel with accessible rooms in St. Louis, Missouri

The St. Louis Union Station Hotel, Curio Collection by Hilton, is a luxurious lodging institution located at 1820 Market Street in the heart of St. Louis, Missouri. This historic hotel is housed in the iconic Union Station building, offering guests a unique and unforgettable experience. The hotel boasts elegant rooms and suites, exquisite dining options, and top-notch amenities, making it the perfect choice for both leisure and business travelers. With its prime location and exceptional service, the St. Louis Union Station Hotel promises a truly memorable stay in the Gateway City.

Holiday Inn Express & Suites St. Louis - Chesterfield, an IHG Hotel, is a modern and comfortable lodging option located in Chesterfield, Missouri. Situated at 11 Arnage Boulevard, this hotel offers a convenient location for both business and leisure travelers. The hotel features spacious and well-appointed rooms and suites, perfect for a relaxing stay. Guests can enjoy amenities such as complimentary breakfast, free Wi-Fi, a fitness center, and an indoor pool. Whether you're visiting for work or pleasure, Holiday Inn Express & Suites St. Louis - Chesterfield is a great choice for your stay in the St. Louis area.

Holiday Inn Express & Suites Festus - South St. Louis, an IHG Hotel, is a comfortable and convenient lodging option located at 1802 Gamel Cemetery Road in Festus, Missouri. Situated in the heart of the South St. Louis area, this hotel offers modern amenities and a welcoming atmosphere for travelers. Guests can enjoy a complimentary breakfast, free Wi-Fi, a fitness center, and an indoor pool during their stay. With easy access to nearby attractions and restaurants, Holiday Inn Express & Suites Festus is the perfect choice for both business and leisure travelers visiting the area.

The Spa at Four Seasons Hotel St. Louis is a luxurious beauty salon, gym, health, and spa located at 999 North 2nd Street in St. Louis, Missouri, United States. Step into our Couple's Spa Suite for a rejuvenating shared experience, complete with a private steam room, shower, and relaxation space. Choose from a wide variety of healing massages and results-oriented facials tailored for women, men, and teens. Treat yourself to manicures, pedicures, and scrubs to pamper your nails. Relax and unwind with curated combinations of treatments for hours of full-body relaxation. Our Fitness Facilities are available for maintaining your wellness routine. Our dedicated team is here to create a memorable evening for couples looking to reconnect. Gain exclusive access to 12,000 square feet of relaxation in our late-night offering, which includes spa treatments, a candle-lit dinner, and more. Experience the ultimate couples date night at The Spa at Four Seasons Hotel St. Louis.

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North is a comfortable and convenient lodging option located at 318 Taylor Road in Hazelwood, Missouri. This hotel is perfect for travelers looking for a relaxing stay near the airport, with easy access to St. Louis attractions. The rooms are clean and spacious, with modern amenities to ensure a comfortable stay. Guests can enjoy complimentary breakfast, free Wi-Fi, and a fitness center. The friendly staff is always ready to assist with any needs, making this hotel a great choice for both business and leisure travelers.

The Quality Inn Florissant-St. Louis is a comfortable and convenient lodging option located at 55 Dunn Road in Florissant, Missouri, United States. This hotel offers a range of amenities including spacious and well-appointed rooms, complimentary breakfast, free Wi-Fi, and a fitness center. Guests can enjoy easy access to nearby attractions such as the St. Louis Zoo, Gateway Arch, and Busch Stadium. Whether you are traveling for business or leisure, the Quality Inn Florissant-St. Louis provides a relaxing and enjoyable stay for all guests.

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel, is a modern and stylish lodging option located at 1100 Lodora Drive in Wentzville, Missouri, United States. This hotel offers comfortable and spacious rooms and suites, perfect for both business and leisure travelers. Guests can enjoy amenities such as complimentary breakfast, a fitness center, an indoor pool, and free Wi-Fi throughout the property. The hotel's convenient location provides easy access to popular attractions in the St. Louis area. Whether you're visiting for work or pleasure, Holiday Inn Express & Suites Wentzville St Louis West is the perfect choice for your stay.

Hampton Inn St. Louis Wentzville is a charming lodging option located at 150 Wentzville Bluffs Drive in the heart of Wentzville, Missouri. This cozy hotel offers comfortable accommodations and modern amenities, making it the perfect choice for both business and leisure travelers. Guests can enjoy spacious rooms, complimentary breakfast, a fitness center, and a refreshing outdoor pool. The hotel's convenient location also provides easy access to local attractions, shopping, and dining options. Whether you are visiting for work or pleasure, Hampton Inn St. Louis Wentzville ensures a relaxing and enjoyable stay.

Experience a luxurious stay at Live! by Loews in St. Louis, Missouri. Located at 799 Clark Avenue, this upscale lodging option offers spacious accommodations and festive cuisine for a memorable holiday season. Book one of our well-appointed suites for extra room, comforts, and amenities, all with Loews' genuine and attentive service included. Situated in Ballpark Village in downtown St. Louis, our hotel is just a short walk away from iconic attractions like Busch Stadium and the America’s Center Convention Complex. With 216 guestrooms, 17,000 sq. ft. of meeting and event space, and four dining outlets, Live! by Loews - St. Louis provides first-class hospitality and superior amenities for both leisure and business travelers.

Super 8 By Wyndham St Louis North is a comfortable and affordable lodging option located at 6200 North Broadway in St. Louis, Missouri. This hotel offers a convenient location for travelers looking to explore the city, with easy access to popular attractions and amenities. The rooms are clean and spacious, providing a relaxing atmosphere for guests to unwind after a day of sightseeing or business meetings. With friendly staff and top-notch service, Super 8 By Wyndham St Louis North is the perfect choice for a pleasant stay in the heart of St. Louis.

Holiday Inn Express St. Louis - Central West End, an IHG Hotel, is a modern and comfortable lodging option located in the vibrant city of St. Louis, Missouri. Situated at 4630 Lindell Boulevard, this hotel offers convenient access to popular attractions such as Forest Park, the St. Louis Zoo, and the iconic Gateway Arch. Guests can enjoy a complimentary breakfast, free Wi-Fi, and access to a fitness center during their stay. With friendly staff and cozy accommodations, Holiday Inn Express is the perfect choice for travelers looking for a relaxing and enjoyable stay in the heart of St. Louis.

Hyatt Regency St. Louis At The Arch is a luxurious lodging institution located at 315 Chestnut Street in the heart of St. Louis, Missouri, United States. Situated just steps away from the iconic Gateway Arch, this hotel offers stunning views of the city skyline and easy access to top attractions. With spacious and elegantly appointed rooms, top-notch amenities, and exceptional service, Hyatt Regency St. Louis At The Arch provides a truly unforgettable stay for both leisure and business travelers. Whether you're visiting for a weekend getaway or a corporate event, this hotel is the perfect choice for a memorable experience in St. Louis.

Located at 4450 Evans Place in St. Louis, Missouri, the Hilton Garden Inn St. Louis Airport is a premier lodging option for travelers visiting the area. This modern and stylish hotel offers comfortable rooms, a fitness center, a restaurant, and a business center. Guests can enjoy convenient access to the nearby airport as well as popular attractions in St. Louis. With friendly staff, great amenities, and a convenient location, the Hilton Garden Inn St. Louis Airport is the perfect choice for both business and leisure travelers.

Quality Inn & Suites Arnold - St Louis is a comfortable and convenient lodging option located in Arnold, Missouri. Situated at 3610 West Outer Road, this hotel offers a range of amenities including spacious rooms, complimentary breakfast, free WiFi, and a fitness center. Guests can enjoy easy access to nearby attractions such as the St. Louis Zoo, Gateway Arch, and Busch Stadium. Whether you are traveling for business or leisure, Quality Inn & Suites Arnold - St Louis provides a welcoming and affordable stay for all visitors.

La Quinta Inn & Suites by Wyndham Festus - St. Louis South is a comfortable and convenient lodging option located at 1001 Veterans Boulevard in Festus, Missouri, United States. The hotel offers a range of amenities including free breakfast, a fitness center, an indoor pool, and free Wi-Fi. The rooms are spacious and well-equipped with modern furnishings, making it a perfect choice for both business and leisure travelers. With its convenient location near St. Louis, guests can easily access popular attractions and dining options in the area. Choose La Quinta Inn & Suites for a relaxing and enjoyable stay in Festus.

Comfort Inn & Suites St. Louis-O'Fallon is a cozy and welcoming lodging option located at 100 Comfort Inn Court in O'Fallon, Missouri. This comfortable hotel offers a range of amenities and services to ensure a pleasant stay for guests. The rooms are spacious and well-appointed, featuring modern decor and all the necessary comforts. Guests can enjoy a complimentary hot breakfast each morning, as well as access to the fitness center and indoor pool. The hotel's convenient location makes it easy to explore the attractions of St. Louis, while also providing a peaceful retreat in the charming town of O'Fallon. Whether you're traveling for business or leisure, Comfort Inn & Suites St. Louis-O'Fallon is a great choice for your stay in the area.

Holiday Inn Express & Suites St. Louis West-O'Fallon is a modern and comfortable lodging option located at 1175 Technology Drive in O'Fallon, Missouri, United States. This hotel offers a convenient location for both business and leisure travelers, with easy access to nearby attractions and corporate offices. The rooms and suites are spacious and well-appointed, featuring amenities such as free Wi-Fi, flat-screen TVs, and plush bedding. Guests can start their day with a complimentary hot breakfast buffet, and stay active in the fitness center or indoor pool. With friendly service and a welcoming atmosphere, Holiday Inn Express & Suites St. Louis West-O'Fallon is the perfect choice for a relaxing stay in the St. Louis area.

Extended Stay America - St. Louis - St. Peters is a comfortable and convenient lodging option located at 5555 Veterans Memorial Parkway in St. Peters, Missouri. This extended stay hotel offers spacious rooms with fully equipped kitchens, free Wi-Fi, and on-site laundry facilities, making it perfect for both short-term and long-term stays. Guests can enjoy easy access to nearby attractions, shopping centers, and restaurants, making it an ideal choice for travelers looking for a home away from home in the St. Louis area.

Super 8 by Wyndham St. Louis Airport is a comfortable and convenient lodging option located at 9798 Saint Charles Rock Road in Breckenridge Hills, Missouri. Just a short drive away from St. Louis Lambert International Airport, this hotel offers easy access to the city's attractions and businesses. The rooms are clean and well-appointed, featuring modern amenities to ensure a pleasant stay for guests. Guests can enjoy complimentary breakfast, free Wi-Fi, and access to a fitness center. Whether traveling for business or leisure, Super 8 by Wyndham St. Louis Airport provides a welcoming and affordable accommodation option for visitors to the area.

HomeTowne Studios St. Louis - Airport/N Lindbergh is a convenient and affordable lodging option located at 6065 North Lindbergh Boulevard in Hazelwood, Missouri. This institution offers comfortable and spacious rooms equipped with all the necessary amenities for a pleasant stay. Whether you are traveling for business or leisure, you will find this hotel to be a convenient choice with its close proximity to the airport and easy access to nearby attractions. Enjoy a comfortable stay at HomeTowne Studios St. Louis - Airport/N Lindbergh during your visit to the St. Louis area.

St. Louis Airport Hotel is a comfortable and convenient lodging option located at 9600 Natural Bridge Road in St. Louis, Missouri. This hotel is perfect for travelers looking for a place to stay near the airport, as it offers easy access to the terminals. The hotel features modern amenities, spacious rooms, and friendly staff to ensure a pleasant stay for guests. Whether you are in town for business or pleasure, St. Louis Airport Hotel is a great choice for your accommodation needs.

Sheraton Westport Plaza Hotel St. Louis is a luxurious lodging option located at 900 West Port Plaza Drive in St. Louis, Missouri, United States. This upscale hotel offers a comfortable and elegant stay for guests visiting the area. With well-appointed rooms, modern amenities, and excellent service, Sheraton Westport Plaza Hotel is the perfect choice for both business and leisure travelers. The hotel also features a fitness center, indoor pool, on-site dining options, and convenient access to nearby attractions. Experience a relaxing and enjoyable stay at Sheraton Westport Plaza Hotel St. Louis.

The Pear Tree Inn St. Louis Airport is a comfortable and convenient lodging option located at 10810 Pear Tree Lane in Saint Ann, Missouri, United States. This welcoming hotel provides guests with a cozy and relaxing atmosphere, perfect for both leisure and business travelers. With its close proximity to the airport, guests can easily access their flights without any hassle. The hotel offers modern amenities, friendly staff, and a complimentary breakfast to ensure a pleasant stay for all visitors. Experience a home away from home at the Pear Tree Inn St. Louis Airport.

Sonesta Simply Suites St Louis Earth City is a cozy and comfortable lodging option located in Earth City, Missouri. Situated at 3250 Rider Trail South, this institution offers spacious suites equipped with modern amenities for a relaxing stay. Whether you are traveling for business or leisure, Sonesta Simply Suites provides a convenient and welcoming environment for guests. With its convenient location and excellent service, this lodging option is the perfect choice for your stay in St Louis.

SpringHill Suites by Marriott St. Louis Airport/Earth City is a modern and stylish lodging option located in St. Louis, Missouri, United States. Situated at 3099 Rider Trail South, this hotel offers convenient access to the nearby airport and other attractions in the area. The spacious suites are beautifully designed and equipped with all the amenities needed for a comfortable stay. Guests can enjoy complimentary breakfast, a fitness center, an indoor pool, and a business center. Whether traveling for business or leisure, SpringHill Suites by Marriott offers a welcoming and relaxing atmosphere for all guests.

Fairfield Inn & Suites by Marriott St. Louis St. Charles is a comfortable and convenient lodging option located at 801 Veterans Memorial Parkway in Saint Charles, Missouri, United States. This hotel offers spacious and modern rooms, a complimentary breakfast buffet, a fitness center, an indoor pool, and free high-speed Wi-Fi. Guests can enjoy easy access to nearby attractions such as the historic Main Street district, Ameristar Casino, and the St. Charles Convention Center. Whether traveling for business or leisure, Fairfield Inn & Suites provides a welcoming and relaxing stay for all guests.

DoubleTree by Hilton St. Louis Airport is a premier lodging destination conveniently located at 4505 Woodson Road in St. Louis, Missouri. This upscale hotel offers modern and comfortable accommodations for travelers seeking a relaxing stay near the airport. The spacious rooms are elegantly decorated and feature luxurious amenities to ensure a pleasant stay. Guests can enjoy delicious dining options at the on-site restaurant, as well as access to a fitness center and indoor pool. With its convenient location and top-notch services, DoubleTree by Hilton St. Louis Airport is the perfect choice for both business and leisure travelers visiting the area.

The Sheraton Westport Chalet Hotel St. Louis is a luxurious lodging destination situated at 191 West Port Plaza Drive in St. Louis, Missouri, United States. This elegant hotel offers sophisticated accommodations, exceptional amenities, and impeccable service to ensure a comfortable and memorable stay for guests. With its convenient location near popular attractions, shopping, and dining options, the Sheraton Westport Chalet Hotel St. Louis is the perfect choice for travelers seeking a relaxing and upscale experience in St. Louis.

Budget Inn - St. Louis is a comfortable and affordable lodging option located at 1405 Dunn Road in St. Louis, Missouri. Conveniently situated in a prime location, this institution offers guests a cozy and welcoming atmosphere. Whether you are traveling for business or pleasure, Budget Inn - St. Louis provides all the amenities you need for a relaxing stay. With friendly staff, clean rooms, and easy access to nearby attractions, Budget Inn - St. Louis is the perfect choice for budget-conscious travelers looking for a comfortable place to stay in St. Louis.

Staybridge Suites St Louis - Westport, an IHG Hotel, is a charming lodging establishment located at 25 Progress Parkway in Maryland Heights, Missouri. This hotel offers comfortable and spacious suites equipped with modern amenities, perfect for both short and extended stays. Guests can enjoy complimentary breakfast, a fitness center, an outdoor pool, and a business center. Conveniently located near Westport Plaza, guests can easily access shopping, dining, and entertainment options. With friendly staff and a welcoming atmosphere, Staybridge Suites St Louis - Westport is the ideal choice for travelers looking for a relaxing and enjoyable stay in the St Louis area.