TOP 30 Best City center lodging in San Antonio, Texas

Welcome to OYO Inn & Suites Medical Center San Antonio! Conveniently located at 3782 Northwest Loop 410, San Antonio, Texas, our hotel is the perfect choice for travelers looking for comfortable and affordable lodging. Our hotel is centrally located close to shopping, the medical center, and the Northwest 410 loop, making it easy to access all that San Antonio has to offer. Whether you're visiting for business or leisure, our clean, spacious rooms are designed with your comfort in mind.

Comfort Inn & Suites Near Medical Center is a cozy and convenient lodging option located in San Antonio, Texas. Situated at 6039 Interstate 10, this hotel is perfect for both leisure and business travelers looking for a comfortable stay near the medical center. The hotel offers spacious and well-appointed rooms, complimentary breakfast, free Wi-Fi, and a fitness center for guests to enjoy. With its prime location and excellent amenities, Comfort Inn & Suites Near Medical Center is the perfect choice for a relaxing stay in San Antonio.

SureStay Plus By Best Western San Antonio North 281 N is a comfortable and convenient lodging option located at 11355 San Pedro Avenue in San Antonio, Texas. This institution offers a cozy and welcoming atmosphere for guests looking for a relaxing stay in the heart of San Antonio. With easy access to Highway 281, guests can easily explore the city's attractions and landmarks. The hotel boasts modern amenities, friendly staff, and spacious rooms to ensure a pleasant stay for all visitors. Whether you are traveling for business or leisure, SureStay Plus By Best Western San Antonio North 281 N is the perfect choice for your accommodation needs.

WoodSpring Suites San Antonio North Live Oak I-35 is a comfortable and affordable lodging option located in San Antonio, Texas. Situated right off Interstate 35, this institution offers convenient access to the city's attractions and amenities. The spacious suites are equipped with kitchens, making it a perfect choice for extended stays or travelers looking for a home away from home. Guests can enjoy amenities such as free WiFi, on-site laundry facilities, and a 24-hour fitness center. Whether visiting for business or pleasure, WoodSpring Suites provides a welcoming and convenient stay for all guests.

La Quinta Inn by Wyndham San Antonio I-35 N at Rittiman Rd is a comfortable and convenient lodging option located in San Antonio, Texas. Situated at 6410 North Interstate 35, this hotel offers easy access to the city's attractions and amenities. Guests can expect clean and spacious rooms, friendly service, and a range of amenities including free breakfast, a swimming pool, and a fitness center. Whether visiting for business or leisure, La Quinta Inn provides a relaxing and enjoyable stay for travelers in the heart of San Antonio.

Econo Lodge Near Lackland Air Force Base-SeaWorld is a comfortable and convenient lodging option located at 2211 Southwest Loop 410 in San Antonio, Texas, United States. Perfect for travelers looking to explore the nearby Lackland Air Force Base or enjoy a day at SeaWorld, this hotel offers affordable rates and cozy accommodations. Guests can expect friendly service, clean rooms, and easy access to popular attractions in the area. Whether visiting for business or pleasure, Econo Lodge Near Lackland Air Force Base-SeaWorld is a great choice for a relaxing stay in San Antonio.

Days Inn by Wyndham San Antonio Splashtown/ATT Center is a comfortable and convenient lodging option located in San Antonio, Texas. Situated at 3443 North PanAm Expressway, this hotel is the perfect choice for travelers looking to explore the city's attractions such as Splashtown water park and the ATT Center. The hotel offers cozy rooms, modern amenities, and friendly service to ensure a pleasant stay for guests. With its central location and affordable rates, Days Inn by Wyndham San Antonio Splashtown/ATT Center is an ideal choice for both leisure and business travelers visiting the area.

Days Inn & Suites by Wyndham San Antonio North/Stone Oak is a comfortable and convenient lodging option located in the heart of San Antonio, Texas. Situated at 1505 Bexar Crossing, this hotel offers a range of amenities and services to ensure a pleasant stay for guests. The spacious rooms and suites are well-appointed with modern furnishings and feature complimentary Wi-Fi, flat-screen TVs, and coffee makers. Guests can also enjoy a complimentary continental breakfast each morning and access to the outdoor pool and fitness center. With its prime location near popular attractions and dining options, Days Inn & Suites by Wyndham San Antonio North/Stone Oak is the perfect choice for both business and leisure travelers.

Days Inn by Wyndham San Antonio Southeast By AT&T Center is a comfortable and conveniently located lodging option in San Antonio, Texas. Situated at 5003 Rigsby Avenue, this hotel offers easy access to the AT&T Center and other popular attractions in the area. The rooms are clean and spacious, featuring modern amenities to ensure a pleasant stay for guests. The friendly staff is always available to assist with any needs or inquiries. Guests can also enjoy complimentary breakfast, free Wi-Fi, and a seasonal outdoor pool. Whether visiting for business or leisure, Days Inn by Wyndham San Antonio Southeast By AT&T Center provides a welcoming and affordable accommodation option in the heart of San Antonio.

Motel 6 San Antonio, TX - Fiesta Trails is a cozy and convenient lodging option located at 9447 Interstate 10 in San Antonio, Texas, United States. This budget-friendly motel offers comfortable rooms and a range of amenities to ensure a pleasant stay for guests. With its prime location near Fiesta Trails, guests can easily access nearby attractions, restaurants, and shopping centers. Whether you're traveling for business or leisure, Motel 6 San Antonio, TX - Fiesta Trails provides a welcoming and affordable accommodation option.

Red Roof Inn San Antonio E – Frost Bank Center is a welcoming lodging facility located at 138 North WW White Road in San Antonio, Texas. Situated near the Frost Bank Center, this hotel offers comfortable rooms and convenient amenities for travelers looking for a relaxing stay in the heart of San Antonio. The hotel provides easy access to popular attractions, dining options, and shopping destinations in the area. Guests can enjoy a pleasant stay with friendly service and affordable rates at Red Roof Inn San Antonio E – Frost Bank Center.

La Quinta Inn & Suites by Wyndham San Antonio The Dominion is a comfortable and modern lodging option located in San Antonio, Texas. Situated conveniently at 25042 Interstate 10, this hotel offers a peaceful retreat for travelers looking to relax and unwind. The rooms are well-appointed with all the necessary amenities to ensure a pleasant stay, and guests can enjoy a complimentary breakfast each morning. The hotel also features a fitness center, outdoor pool, and free Wi-Fi for added convenience. Whether visiting for business or pleasure, La Quinta Inn & Suites by Wyndham San Antonio The Dominion provides a welcoming and convenient home away from home.

Located at 4 Piano Place in San Antonio, Texas, the Quality Inn Near Medical Center is the perfect choice for travelers seeking comfortable and convenient lodging. Situated near the medical center, this hotel offers easy access to top healthcare facilities in the area. The rooms are spacious and well-appointed, with modern amenities to ensure a pleasant stay. Guests can enjoy a complimentary breakfast each morning and access to the outdoor pool and fitness center. With friendly staff and a prime location, the Quality Inn Near Medical Center is an excellent option for both business and leisure travelers in San Antonio.

La Quinta Inn by Wyndham San Antonio Lackland is a comfortable and convenient lodging option located at 6511 Military Drive West in San Antonio, Texas. Situated near Lackland Air Force Base, this hotel offers easy access to popular attractions such as SeaWorld San Antonio and the River Walk. Guests can enjoy spacious rooms with modern amenities, a complimentary breakfast, and a refreshing outdoor swimming pool. Whether visiting for business or leisure, La Quinta Inn by Wyndham San Antonio Lackland provides a welcoming and relaxing stay for all travelers.

Motel 6 San Antonio, TX Six Flags Fiesta TX/LA Cantera Area is a comfortable and budget-friendly lodging option conveniently located at 16500 Interstate 10 in San Antonio, Texas. Situated near popular attractions such as Six Flags Fiesta Texas and the upscale shopping destination La Cantera, this motel is the perfect choice for travelers looking to explore the vibrant city of San Antonio. With clean and spacious rooms, friendly staff, and easy access to nearby dining and entertainment options, Motel 6 San Antonio provides a convenient and affordable stay for guests visiting the area.

Motel 6 San Antonio, TX - Northwest Medical Center is a comfortable and convenient lodging option located at 9400 Wurzbach Road in San Antonio, Texas. Situated near the Northwest Medical Center, this motel is the perfect choice for those visiting loved ones in the hospital or seeking medical treatment. The rooms are clean and cozy, with all the necessary amenities for a relaxing stay. Guests can enjoy free Wi-Fi, complimentary morning coffee, and a refreshing outdoor pool. The friendly staff is always ready to assist with any needs or questions. Whether you are in town for medical reasons or simply exploring the vibrant city of San Antonio, Motel 6 is a great choice for affordable and comfortable accommodation.

Super 8 by Wyndham San Antonio/Fiesta is a comfortable and convenient lodging option located at 5319 Casa Bella Street in San Antonio, Texas. Situated near the popular Fiesta Texas theme park, this hotel offers easy access to attractions, dining, and shopping in the area. Guests can enjoy clean and spacious rooms, free breakfast, and a range of amenities including an outdoor pool and fitness center. Whether visiting for business or leisure, Super 8 by Wyndham San Antonio/Fiesta provides a welcoming and affordable stay in the heart of Texas.

Super 8 by Wyndham San Antonio Pearl District/Downtown is a cozy and convenient lodging option located in the vibrant city of San Antonio, Texas, United States. Situated in the trendy Pearl District, this hotel offers easy access to downtown attractions, including the iconic River Walk and the historic Alamo. Guests can enjoy comfortable rooms, complimentary breakfast, and a range of amenities to ensure a pleasant stay. Whether visiting for business or leisure, Super 8 by Wyndham San Antonio Pearl District/Downtown provides a welcoming and affordable accommodation option in the heart of the city.

Baymont by Wyndham San Antonio Near South Texas Medical Ctr is a comfortable and convenient lodging option located at 9542 Interstate 10 in San Antonio, Texas. Situated near the South Texas Medical Center, this hotel offers easy access to medical facilities and is also close to popular attractions such as Six Flags Fiesta Texas and the San Antonio River Walk. The hotel features modern and spacious rooms, a fitness center, outdoor pool, complimentary breakfast, and free WiFi. Whether you are visiting for business or leisure, Baymont by Wyndham San Antonio Near South Texas Medical Ctr provides a relaxing and welcoming stay for all guests.

Days Inn by Wyndham San Antonio is a cozy and convenient lodging option located at 9401 North Interstate 35 in San Antonio, Texas. This budget-friendly hotel offers comfortable rooms and a range of amenities to make your stay enjoyable, including free breakfast, WiFi, and parking. The hotel is conveniently located near popular attractions such as the Alamo, River Walk, and Six Flags Fiesta Texas. Whether you are visiting for business or leisure, Days Inn by Wyndham San Antonio provides a welcoming and affordable accommodation option in the heart of Texas.

Americas Best Value Inn - Frost Bank Center is a comfortable and convenient lodging option located in San Antonio, Texas. Situated at 3645 North PanAm Expressway, this inn offers guests easy access to the city's attractions and amenities. The Frost Bank Center provides a range of amenities and services to ensure a pleasant stay, including spacious rooms, free breakfast, and a convenient location near the highway. Whether you are visiting for business or pleasure, Americas Best Value Inn - Frost Bank Center is a great choice for your accommodation needs in San Antonio.

Econo Lodge San Antonio Northeast I-35 is a cozy and affordable lodging option located conveniently at 9503 North Interstate 35 in San Antonio, Texas. This institution offers comfortable rooms, modern amenities, and a convenient location for travelers looking to explore the vibrant city of San Antonio. Whether you are visiting for business or leisure, Econo Lodge San Antonio Northeast I-35 provides a welcoming atmosphere and excellent service to make your stay enjoyable. With easy access to major attractions, dining options, and shopping centers, this hotel is the perfect choice for your stay in San Antonio.

Super 8 San Antonio/ATT Center/Coliseum Area is a convenient and comfortable lodging option located at 3617 North PanAm Expressway in San Antonio, Texas. Just minutes away from popular attractions such as the ATT Center and the Coliseum, this hotel is the perfect choice for travelers looking to explore the vibrant city of San Antonio. With clean and cozy rooms, friendly staff, and affordable rates, Super 8 San Antonio/ATT Center/Coliseum Area ensures a pleasant stay for both business and leisure travelers. Book your stay today and experience the best of San Antonio hospitality.

Days Inn by Wyndham San Antonio/Near Lackland AFB is a comfortable and convenient lodging option located at 6815 West US Highway 90 in San Antonio, Texas, United States. This hotel is ideal for visitors looking for a place to stay near Lackland Air Force Base. The rooms are clean and well-equipped with modern amenities to ensure a pleasant stay. Guests can enjoy complimentary breakfast, free Wi-Fi, and access to a fitness center. The hotel's prime location offers easy access to popular attractions in the area. Whether you are visiting for business or leisure, Days Inn by Wyndham San Antonio/Near Lackland AFB is a great choice for your accommodation needs.

Econo Lodge Downtown South is a cozy and affordable lodging option located at 606 Division Avenue in San Antonio, Texas. Situated in a convenient location, guests can easily access popular attractions such as the River Walk, The Alamo, and the San Antonio Missions. The hotel offers comfortable rooms with modern amenities, complimentary breakfast, and free Wi-Fi. Whether you are visiting for business or leisure, Econo Lodge Downtown South provides a welcoming and convenient stay for all travelers.

Super 8 by Wyndham San Antonio at I-10 is a cozy and convenient lodging option located at 222 South WW White Road in San Antonio, Texas. Situated just off Interstate 10, this hotel offers easy access to popular attractions such as the Alamo, River Walk, and Six Flags Fiesta Texas. Guests can enjoy comfortable rooms equipped with modern amenities, complimentary breakfast, and free Wi-Fi. Whether traveling for business or leisure, Super 8 by Wyndham San Antonio at I-10 provides a welcoming and affordable stay for all visitors.

Travelodge by Wyndham San Antonio Lackland AFB is a comfortable and convenient lodging option located at 6861 West US Highway 90 in San Antonio, Texas. Situated near Lackland Air Force Base, this hotel offers easy access to popular attractions such as SeaWorld San Antonio and the Alamo. The rooms are clean and well-appointed, featuring modern amenities such as free Wi-Fi and flat-screen TVs. Guests can enjoy a complimentary breakfast each morning and relax in the outdoor pool. With its friendly staff and affordable rates, Travelodge by Wyndham San Antonio Lackland AFB is the perfect choice for both business and leisure travelers.

Knights Inn San Antonio near Frost Bank Center is a cozy and convenient lodging option located in the heart of San Antonio, Texas. Situated at 4039 East Houston Street, this hotel is just a stone's throw away from the Frost Bank Center, making it an ideal choice for business travelers and tourists alike. The hotel offers comfortable rooms, friendly service, and easy access to all the attractions and amenities that San Antonio has to offer. Whether you're in town for work or play, Knights Inn San Antonio near Frost Bank Center provides a welcoming and affordable stay for all guests.

Travel Inn San Antonio is a cozy and welcoming lodging establishment located at 5710 Industry Park Drive in San Antonio, Texas. Our convenient location offers easy access to popular attractions, dining options, and shopping centers in the area. Whether you are visiting for business or leisure, our comfortable rooms and friendly staff will ensure you have a pleasant stay. Amenities include free Wi-Fi, parking, and continental breakfast. Book your stay with us and experience the comfort and convenience of Travel Inn San Antonio.

Days Inn by Wyndham San Antonio Alamo/Riverwalk is a charming lodging located at 400 Bowie Street in the heart of San Antonio, Texas. Just a short distance from the iconic Alamo and the vibrant Riverwalk, this hotel offers guests a convenient and comfortable stay in a prime location. The hotel features cozy rooms, modern amenities, and friendly service to ensure a pleasant stay for all guests. Whether you are visiting for business or leisure, Days Inn by Wyndham San Antonio Alamo/Riverwalk is the perfect choice for your stay in this historic city.