TOP 10 Luxury hotel rooms in Barnstable, Massachusetts

Hyannis Plaza Hotel is a charming lodging facility located at 662 Main Street in the heart of Barnstable, Massachusetts. The hotel offers comfortable and well-appointed rooms, friendly service, and convenient amenities for both business and leisure travelers. Guests can enjoy easy access to the nearby attractions, shopping, and dining options in the area. Whether you are visiting for a weekend getaway or a business trip, Hyannis Plaza Hotel provides a relaxing and enjoyable stay in a prime location.

The Best Western Cape Cod Hotel is a charming lodging establishment located at 1470 Iyannough Road in Barnstable, Massachusetts, United States. Situated on beautiful Cape Cod, this hotel offers comfortable accommodations and top-notch amenities for guests looking to explore the area. With a convenient location near popular attractions, shopping, and dining options, the Best Western Cape Cod Hotel is the perfect choice for travelers seeking a relaxing and enjoyable stay on the Cape. Whether you are visiting for business or pleasure, this hotel provides a welcoming atmosphere and excellent service to make your stay memorable.

The Hyannis Harbor Hotel is a charming lodging establishment located at 213 Ocean Street in Barnstable, Massachusetts, United States. Situated near the picturesque Hyannis Harbor, this hotel offers guests a comfortable and convenient stay with its cozy rooms and friendly staff. The hotel provides easy access to the beach, shopping, dining, and other attractions in the area. Whether you are visiting for business or pleasure, the Hyannis Harbor Hotel is the perfect choice for your stay in Cape Cod.

Anchor In is a charming lodging institution located at 1 South Street in the picturesque town of Barnstable, Massachusetts. Nestled along the coast, this cozy retreat offers comfortable accommodations with stunning views of the harbor. Guests can relax and unwind in the well-appointed rooms, enjoy a delicious breakfast each morning, and take advantage of the convenient location near local shops, restaurants, and attractions. Whether you're looking for a peaceful getaway or a romantic escape, Anchor In provides the perfect setting for a memorable stay on the Cape.

Cape Cod Inn is a charming hotel located in the heart of Hyannis, Massachusetts. Situated on Main Street in Barnstable, this cozy inn offers comfortable lodging and delicious dining options for guests visiting the Cape Cod area. With a convenient location near local attractions and the beautiful beaches of Cape Cod, Cape Cod Inn is the perfect place to relax and unwind during your stay. Whether you're looking for a comfortable room, a delicious meal at the on-site restaurant, or just a welcoming atmosphere, Cape Cod Inn has everything you need for a memorable vacation experience.

Comfort Inn Hyannis - Cape Cod is a cozy and inviting lodging option located at 259 Main Street in Barnstable, Massachusetts. Situated in the heart of Cape Cod, this hotel offers comfortable accommodations and convenient amenities for both leisure and business travelers. Guests can enjoy a complimentary breakfast, free wifi, a fitness center, and a seasonal outdoor pool. The hotel's central location provides easy access to nearby attractions such as beaches, shopping, dining, and entertainment options. Whether you are visiting for a weekend getaway or an extended stay, Comfort Inn Hyannis - Cape Cod is the perfect choice for a relaxing and enjoyable stay on the beautiful Cape Cod peninsula.

The Courtyard by Marriott Cape Cod Hyannis is a charming lodging destination situated at 707 Iyannough Road in Barnstable, Massachusetts, United States. This hotel offers comfortable and modern accommodations for guests looking to explore the beautiful Cape Cod area. With spacious rooms, a fitness center, indoor pool, and on-site dining options, the Courtyard by Marriott Cape Cod Hyannis provides a relaxing and convenient stay for travelers of all kinds. Whether visiting for business or pleasure, guests can enjoy the hotel's close proximity to local attractions, shopping, and dining options. Experience comfort and hospitality at its finest at the Courtyard by Marriott Cape Cod Hyannis.

Sea Street Inn is a charming lodging establishment located at 328 Sea Street in Barnstable, Massachusetts, United States. This cozy inn offers comfortable accommodations and a warm, welcoming atmosphere for guests looking to relax and unwind by the sea. With its convenient location near the beach and local attractions, Sea Street Inn is the perfect destination for a peaceful getaway on Cape Cod. Enjoy a cozy room, friendly service, and a memorable stay at this quaint seaside retreat.

Fairfield Inn & Suites by Marriott Cape Cod Hyannis is a charming lodging establishment located at 867 Iyannough Road in Barnstable, Massachusetts, United States. Situated in the heart of Cape Cod, this hotel offers comfortable accommodations and modern amenities for travelers looking to explore the beautiful surroundings. The hotel features spacious rooms and suites, a complimentary breakfast buffet, a fitness center, an indoor pool, and free Wi-Fi. With its convenient location and friendly staff, Fairfield Inn & Suites by Marriott Cape Cod Hyannis is the perfect choice for a relaxing stay on the Cape.

Skyfield Bed and Breakfast is a charming lodging establishment located at 151 Main Street in the picturesque town of Barnstable, Massachusetts. Nestled in a tranquil setting, guests can enjoy the peaceful ambiance and beautiful surroundings. The cozy rooms are tastefully decorated and offer a comfortable stay for visitors. The friendly staff provides top-notch service and ensures that guests have a memorable experience during their stay. Whether you are visiting for a relaxing getaway or exploring the local attractions, Skyfield Bed and Breakfast is the perfect place to call home during your travels.

The Cape Cod Irish Village at The Emerald Resort & Conference Center is a charming establishment located in the heart of Barnstable, Massachusetts. This unique institution offers a cozy and welcoming atmosphere for guests to enjoy a wide range of amenities, including a traditional Irish bar, delicious food, comfortable lodging, a top-rated restaurant, and a luxurious spa. Whether you're looking to relax and unwind or indulge in some Irish hospitality, the Cape Cod Irish Village has everything you need for a memorable stay. Come experience the magic of Ireland right here in the United States at 35 Scudder Avenue.

The Ocean View is a charming lodging establishment located at 966 Craigville Beach Road in Barnstable, Massachusetts. This unique institution offers guests a breathtaking water view from every room, providing a tranquil and relaxing stay. With easy access to Craigville Beach on Nantucket Sound, guests can enjoy the soft sand and warm water temperatures for a perfect beach getaway. In addition to its prime beachfront location, The Ocean View is conveniently situated near popular Cape Cod attractions and historical sites. Guests can also experience exciting events such as the Hyannis Sprint Triathlons and the Best Buddies Challenge right outside their door.

The Captain David Kelley House is a charming and historic lodging located at 539 Main Street in Barnstable, Massachusetts. This beautiful inn offers a cozy and welcoming atmosphere, with elegantly appointed rooms and modern amenities. Guests can enjoy a delicious homemade breakfast each morning and relax in the peaceful surroundings of the inn's garden. The Captain David Kelley House is the perfect place to stay for a relaxing getaway on Cape Cod.

Sea Breeze Inn beach rentals is a charming lodging located at 270 Ocean Avenue in Barnstable, Massachusetts, United States. Situated near the beautiful coastline, this institution offers cozy and comfortable accommodations for guests looking to enjoy a relaxing beach getaway. With a serene atmosphere and stunning ocean views, Sea Breeze Inn is the perfect destination for those seeking a peaceful retreat by the sea. Whether you're looking to unwind on the beach, explore the nearby attractions, or simply relax in the comfort of your room, Sea Breeze Inn beach rentals provides a warm and welcoming stay for all visitors.

The Lamb and Lion Inn, located at 2504 Main Street in Barnstable, Massachusetts, is a classic Cape Cod inn with the spirit of a small luxury hotel. It has been recognized as one of the top 12 pet-friendly properties in the world, making it the perfect destination for travelers with furry friends. The inn offers ultimate guest privacy with multiple separate entrances and exits, ensuring a peaceful and relaxing stay. Situated on 4 acres in historic Cape Cod Bay, the inn is just minutes away from Barnstable Village's shops, restaurants, waterfront dining, and whale watch boat. Guests can also enjoy a short walk to a sunset beach and hiking trails, as well as a ten-minute drive to the island ferries and Hyannis' nightlife. The inn dates back to a 1740 farmhouse with horse stables that have been converted into suites, and features the original 1740 Barn and a central courtyard for a fun and relaxed atmosphere.

DoubleTree by Hilton Cape Cod - Hyannis is a charming lodging institution located in the heart of Barnstable, Massachusetts. Situated at 287 Iyannough Road, this hotel offers a warm and welcoming atmosphere for guests to relax and unwind. The hotel features modern amenities, comfortable accommodations, and exceptional service to ensure a memorable stay. With its convenient location, guests can easily explore the beautiful Cape Cod area and all it has to offer. Whether visiting for business or leisure, DoubleTree by Hilton Cape Cod - Hyannis is the perfect choice for a comfortable and enjoyable stay.

Old Hundred House is a charming lodging establishment located at 1211 Craigville Beach Road in Barnstable, Massachusetts. This historic inn offers a cozy and welcoming atmosphere for guests looking to experience the beauty of Cape Cod. With its quaint rooms and friendly staff, Old Hundred House provides a peaceful retreat for travelers seeking a relaxing getaway. Conveniently situated near the beach, guests can enjoy the natural beauty of the area while also being close to local attractions and activities. Whether you're looking for a romantic escape or a family vacation, Old Hundred House is the perfect choice for your stay in Barnstable.

Courtyard Resort is a charming lodging institution located at 125 North Street in the picturesque town of Barnstable, Massachusetts. Nestled in the heart of Cape Cod, this resort offers a peaceful and relaxing escape for guests looking to unwind and recharge. The resort features comfortable and well-appointed rooms, a sparkling outdoor pool, and a cozy courtyard where guests can enjoy a morning coffee or an evening cocktail. With its convenient location near the beach, shopping, and dining options, Courtyard Resort is the perfect home base for exploring all that Cape Cod has to offer. Whether you're seeking a romantic getaway or a family vacation, Courtyard Resort provides a welcoming and comfortable atmosphere for all guests.

Cape Cod Harbor House Inn is a charming lodging located at 119 Ocean Street in Barnstable, Massachusetts. Situated in the picturesque Cape Cod area, this inn offers cozy and comfortable accommodations with a touch of New England charm. Guests can enjoy beautiful views of the harbor and easy access to nearby attractions, shops, and restaurants. The inn provides a relaxing and welcoming atmosphere, perfect for a weekend getaway or a longer stay on the Cape. With its convenient location and friendly staff, Cape Cod Harbor House Inn is the ideal choice for travelers looking to experience the beauty and hospitality of Cape Cod.

Cape Winds Resort is a charming lodging establishment located at 657 West Main Street in Barnstable, Massachusetts, United States. Situated in a picturesque coastal town, this resort offers comfortable accommodations with stunning views of the surrounding area. Guests can enjoy a relaxing stay in well-appointed rooms, take a dip in the outdoor pool, or explore the nearby beaches and attractions. With its convenient location and friendly staff, Cape Winds Resort is the perfect destination for a memorable vacation on Cape Cod.

Simmons Homestead Inn is a charming lodging establishment located at 288 Scudder Avenue in Barnstable, Massachusetts. This historic inn offers a cozy and welcoming atmosphere for guests looking to experience the beauty of Cape Cod. The inn features comfortable rooms, delicious homemade breakfasts, and friendly hospitality from the owners. With its convenient location near beaches, shopping, and dining options, Simmons Homestead Inn is the perfect choice for a relaxing getaway in Cape Cod.

Saltwinds Bed & Breakfast and Guest House is a charming lodging establishment located at 319 Sea Street in Barnstable, Massachusetts. Situated in a picturesque coastal town, this cozy guest house offers a relaxing and peaceful retreat for travelers looking to escape the hustle and bustle of city life. The rooms are tastefully decorated and equipped with modern amenities to ensure a comfortable stay. Guests can enjoy a delicious homemade breakfast each morning and unwind in the beautiful garden area. With its warm hospitality and serene atmosphere, Saltwinds Bed & Breakfast and Guest House is the perfect destination for a tranquil getaway on Cape Cod.

The Mains'l is a charming lodging institution located at 535 Ocean Street in Barnstable, Massachusetts. Offering a cozy and comfortable stay, this establishment is perfect for travelers looking for a peaceful retreat by the sea. With its convenient location and welcoming atmosphere, The Mains'l is the ideal choice for those seeking a relaxing getaway on the picturesque coast of Massachusetts.

Beechwood Manor is a charming lodging institution located at 2839 Main Street in Barnstable, Massachusetts, United States. Nestled in a picturesque setting, Beechwood Manor offers guests a cozy and comfortable stay in a historic building. With its warm hospitality and beautiful surroundings, Beechwood Manor is the perfect retreat for travelers looking to relax and unwind. Whether you are visiting for a weekend getaway or an extended stay, Beechwood Manor welcomes you with open arms and promises a memorable experience.

Cape Cod Ocean Manor is a charming lodging establishment located at 543 Ocean Street in Barnstable, Massachusetts, United States. Situated just steps away from the beautiful shores of Cape Cod, this cozy retreat offers guests a peaceful and relaxing stay. The Manor features comfortable accommodations, stunning ocean views, and convenient access to local attractions and activities. Whether you're seeking a romantic getaway or a family vacation, Cape Cod Ocean Manor is the perfect destination for a memorable stay on the Massachusetts coast.

Hillcrest Bed & Breakfast is a charming New England residence located at 70 Gosnold Street in Barnstable, Massachusetts. Originally built in 1899, the Hillcrest has a rich history as a guest house, family residence, and now as a weekly rental. The property offers four beautifully decorated guest rooms named The Blueberry Patch, The Ocean Breeze, The Sand Dunes, and Bayberry Brambles. Guests can enjoy their breakfast on the porch, front or back patio, or small deck off the kitchen while listening to the birds and feeling the cool ocean breezes just two blocks away. For those who prefer not to cook, there are plenty of dining options within walking distance, including the Landing Cafe at the nearby ferry dock.

Heritage House Inn is a charming lodging establishment located at 540 Old Colony Road in Barnstable, Massachusetts. This cozy inn offers a peaceful and relaxing retreat for guests looking to experience the historic charm of Cape Cod. With comfortable accommodations, friendly staff, and convenient amenities, Heritage House Inn is the perfect choice for a memorable stay in this beautiful coastal town. Whether you are visiting for a weekend getaway or an extended vacation, you will feel right at home at Heritage House Inn.

Everleigh Cape Cod is a premier 55 active adult community located in the vibrant cultural center of Hyannis, Barnstable. Our community offers luxurious apartments for seniors looking for a fulfilling lifestyle on Cape Cod. With easy access to charming boutique shops, galleries, and a variety of dining options on Main Street, Hyannis provides the perfect backdrop for our residents to enjoy their golden years. Explore over 100 miles of stunning beaches along Cape Cod Bay and Nantucket Sound, then return home to our resort-style amenities including a Pub Lounge, Fitness Center, pool, and Pickle Ball court. Socialize with friends in our Game Room or around the Fire Pit, and embrace the vibrant social life that Everleigh Cape Cod has to offer. Designed specifically for adults over 55, our community ensures a healthy balance of living, community engagement, and the opportunity to forge new friendships. Make Everleigh Cape Cod your home and experience the enriching lifestyle you deserve in the heart of Cape Cod.