The 30 Best Illinois food spots in Murphysboro, Illinois

Domino's Pizza is a popular food institution located at 125 Muddy Monster Rd in Murphysboro, Illinois, United States. Known for their delicious pizzas, they offer meal delivery, meal takeaway, and dine-in options for customers. With a wide variety of toppings and crust options to choose from, Domino's Pizza is a go-to spot for pizza lovers in the area. Whether you're looking for a quick bite to eat or a family meal, Domino's Pizza has something for everyone.

Cindy B's Cafe is a cozy and welcoming restaurant located at 1110 Locust Street in Murphysboro, Illinois. Serving up delicious comfort food with a homestyle touch, this cafe is a favorite spot for locals and visitors alike. From hearty breakfasts to savory lunches, Cindy B's offers a menu full of mouthwatering options that will satisfy any craving. Stop by for a warm and friendly dining experience at Cindy B's Cafe.

The Masters Restaurant & Bar is a cozy and inviting dining establishment located at 5776 Country Club Road in Murphysboro, Illinois. This popular restaurant offers a diverse menu of delicious food and refreshing drinks in a relaxing atmosphere. Whether you're looking for a casual lunch with friends or a special dinner with loved ones, The Masters Restaurant & Bar is the perfect spot to enjoy a memorable dining experience. With friendly service and mouthwatering dishes, this institution is sure to become a favorite destination for locals and visitors alike.

Taqueria Jimenez is a popular Mexican restaurant located at 1508 Walnut Street in Murphysboro, Illinois. Known for its authentic and flavorful Mexican cuisine, Taqueria Jimenez offers a wide variety of tacos, burritos, quesadillas, and other traditional dishes. The restaurant has a cozy and casual atmosphere, perfect for enjoying a delicious meal with friends and family. With friendly staff and affordable prices, Taqueria Jimenez is a favorite spot for locals and visitors alike looking for a taste of Mexico in the heart of Illinois.

El Jalisco is a charming Mexican restaurant located at 501 North 14th Street in Murphysboro, Illinois. This institution offers a warm and inviting atmosphere where guests can enjoy delicious and authentic Mexican cuisine. From savory tacos and enchiladas to flavorful fajitas and refreshing margaritas, El Jalisco has something for everyone to enjoy. Whether you're looking for a casual dinner with friends or a special celebration, El Jalisco is the perfect spot to satisfy your cravings for flavorful Mexican dishes. Come visit us and experience the taste of Mexico right here in Murphysboro.

Small Town Scoop is a charming food store located at 1400 Walnut Street in Murphysboro, Illinois. This quaint institution offers a variety of delicious treats, including homemade ice cream, freshly baked pastries, and gourmet coffee. Whether you're looking for a sweet treat to satisfy your cravings or a cozy spot to relax with a hot beverage, Small Town Scoop is the perfect destination. With its friendly atmosphere and mouthwatering offerings, this local gem is a must-visit for anyone in the area.

Sergio's Mexican Restaurant is a popular dining destination located at 550 East Industrial Park Road in Murphysboro, Illinois. This vibrant eatery offers a delectable range of authentic Mexican cuisine, prepared with fresh ingredients and traditional recipes. From sizzling fajitas to flavorful tacos and refreshing margaritas, Sergio's Mexican Restaurant promises a memorable dining experience for guests of all ages. Whether you're craving a hearty burrito or a zesty enchilada, this restaurant is sure to satisfy your appetite for delicious Mexican fare. Visit Sergio's Mexican Restaurant today and indulge in a taste of Mexico right here in the heart of Illinois.

Molly's Pint Brewpub is a cozy and inviting establishment located in Murphysboro, Illinois. This brewpub offers a wide selection of craft beers brewed on-site, as well as delicious food options to pair with your drink of choice. Whether you're looking to unwind after a long day or catch up with friends over a pint, Molly's Pint Brewpub is the perfect spot. With its friendly staff and laid-back atmosphere, you'll feel right at home at this charming bar and restaurant. Visit us at 12 North 13th Street for a memorable dining and drinking experience.

Mi Patio Mexican Grill is a vibrant and authentic Mexican restaurant located in Murphysboro, Illinois. Situated at 13693 Illinois 149, this establishment offers a warm and inviting atmosphere where guests can enjoy delicious Mexican cuisine and refreshing drinks. Whether you're in the mood for traditional tacos, sizzling fajitas, or flavorful margaritas, Mi Patio Mexican Grill has something for everyone. Come experience a taste of Mexico right in the heart of Illinois at this bustling bar and restaurant.

Taco Bell is a popular fast food restaurant located at 515 Walnut Street in Murphysboro, Illinois. Known for its delicious and affordable Mexican-inspired menu items, Taco Bell offers a wide variety of tacos, burritos, and nachos for customers to enjoy. Whether you're looking for a quick meal on-the-go or a place to sit down and enjoy a tasty dinner, Taco Bell has something for everyone. With friendly staff and a convenient location, Taco Bell is the perfect spot for a satisfying meal takeaway experience.

The Midland Inn is a cozy and inviting bar, food, and restaurant located at 7570 Old Highway 13 in Murphysboro, Illinois. Known for its friendly atmosphere and delicious food, the Midland Inn is a popular spot for locals and visitors alike. Whether you're looking to grab a drink with friends, enjoy a tasty meal, or simply relax and unwind, the Midland Inn has something for everyone. With a diverse menu featuring classic American dishes and a wide selection of drinks, you're sure to find something to satisfy your cravings. Come on in and experience the warmth and charm of the Midland Inn for yourself!

St. Nicholas Brewing Co. MDH is a cozy and inviting restaurant located at 665 North Airport Road in Murphysboro, Illinois. Known for its delicious food and craft beers, this institution offers a unique dining experience for locals and visitors alike. The menu features a variety of dishes made with fresh, locally sourced ingredients, as well as a rotating selection of handcrafted beers brewed on site. Whether you're looking for a casual meal with friends or a special night out, St. Nicholas Brewing Co. MDH is the perfect place to enjoy great food and drinks in a laid-back atmosphere.

Old Rome is a cozy and inviting bar located at 803 North 9th Street in Murphysboro, Illinois. Step into this historic establishment and experience a taste of old-world charm in the heart of the United States. With its warm atmosphere, friendly staff, and wide selection of drinks, Old Rome is the perfect spot to relax and unwind with friends or meet new people. Whether you're looking for a cold beer after a long day or a delicious cocktail to sip on, Old Rome has something for everyone. Come visit us and see why Old Rome is a favorite among locals and visitors alike.

Brews Brothers Taproom is a cozy bar located at 1105 Chestnut Street in Murphysboro, Illinois. With a wide selection of craft beers on tap and a laid-back atmosphere, it's the perfect spot to unwind and enjoy a drink with friends. The friendly staff and inviting decor make Brews Brothers Taproom a favorite among locals and visitors alike. Whether you're a beer enthusiast or just looking for a fun night out, this bar is sure to have something for everyone. So come on in, grab a pint, and relax at Brews Brothers Taproom.

Big Muddy Brewing is a popular food institution located in Murphysboro, Illinois. Situated at 1430 North 7th Street, this brewery offers a unique dining experience with a focus on delicious food and handcrafted beers. Whether you're looking for a casual meal or a place to unwind with friends, Big Muddy Brewing has something for everyone. Come and enjoy the cozy atmosphere, friendly service, and mouthwatering dishes at this must-visit spot in the heart of Murphysboro.

River Rats is a lively bar located at 1603 Walnut Street in Murphysboro, Illinois. Known for its friendly atmosphere and great drinks, River Rats is a popular spot for locals and visitors alike. Whether you're looking to catch up with friends over a cold beer or enjoy live music on the weekends, River Rats has something for everyone. Come on down and experience the fun and excitement at this beloved neighborhood institution.