Charles F. Zorumski, MD

Charles F. Zorumski, MD is a health institution located at 4940 Children's Place in St. Louis, Missouri, United States. Specializing in the treatment of treatment-refractory depression, the institution offers services such as Electroconvulsive therapy and Brain Stimulation Methods. The laboratory at Charles F. Zorumski, MD focuses on the physiology and pharmacology of amino acid neurotransmitters, particularly the regulation of responses at glutamate and GABA receptors. Research studies include the modulation of NMDA and AMPA/kainate classes of glutamate receptors, as well as the role of glutamate receptors in synaptic transmission and long-term potentiation in the hippocampus. Clinical studies are also conducted to examine the benefits and risks of Electroconvulsive therapy in patients with psychiatric disorders. Additionally, the institution provides facilities for preparing in vitro hippocampal cell cultures and electrophysiological recording from cultured cells, tissue slices, or living animals. Collaborations with NIMH include research on Oxysterols and NMDAR Function, as well as Neurosteroids & Proximal Inhibition in the Hippocampus.