TOP 30 Best Seafood cuisine in South Carolina

Southern Seafood & Diet is a cozy and inviting restaurant located at 2237 Charleston Highway in Cayce, South Carolina. Specializing in delicious seafood dishes and healthy diet options, this establishment offers a unique dining experience for those looking to enjoy a satisfying meal. With a menu that caters to both seafood lovers and health-conscious individuals, Southern Seafood & Diet is the perfect spot to indulge in flavorful and nutritious cuisine. Whether you're craving a seafood feast or a light and wholesome meal, this restaurant has something for everyone. Come dine with us and experience the best of Southern cuisine with a healthy twist.

Flowers Seafood Co is a renowned seafood institution located on Edisto Island, South Carolina. Situated at 1914 South Carolina 174, this family-owned establishment offers a wide variety of fresh, locally sourced seafood. From succulent shrimp and flavorful oysters to delicious crab and fish, Flowers Seafood Co is a must-visit destination for seafood lovers. With a commitment to quality and customer satisfaction, this institution provides a true taste of the South Carolina coast. Visit Flowers Seafood Co for a memorable dining experience that celebrates the bounty of the sea.

Dry Dock Seafood is a charming restaurant located in Mullins, South Carolina, offering a delicious and diverse menu of fresh seafood dishes. Situated at 3137 U.S. 76, this institution is a popular dining destination for locals and visitors alike. With a cozy and welcoming atmosphere, Dry Dock Seafood is the perfect place to enjoy a casual meal with family and friends. From succulent shrimp and flavorful fish to mouthwatering crab cakes and hearty seafood platters, there is something for every seafood lover to enjoy. Come and indulge in a gastronomic experience at Dry Dock Seafood, where the flavors of the sea are brought to life in every dish.

Clark's Seafood and Chop House is a cozy and inviting bar and restaurant located in Little River, South Carolina. Situated at 720 Highway 17, this establishment offers a wide selection of fresh seafood and succulent chops for guests to enjoy. The warm and welcoming atmosphere, paired with exceptional service, makes Clark's the perfect spot for a delicious meal with friends and family. Whether you're in the mood for a perfectly cooked steak or a platter of mouthwatering seafood, Clark's Seafood and Chop House has something for everyone. Come and experience the flavors of the South at this charming eatery.

Captain Steve's Family Seafood Restaurant in Fort Mill, SC is a beloved local institution that has been serving up the freshest seafood since 1996. Owner Steve Mantekas is committed to providing top quality food and service, making Captain Steve's a favorite destination for seafood lovers in the Charlotte area. Located at 1975 U.S. 21 in Fort Mill, South Carolina, Captain Steve's offers a diverse menu of American classics with a focus on fresh seafood. Whether you're in the mood for succulent oysters, classic sandwiches, or hearty entrees, there's something for everyone at this family-owned and operated restaurant.

Michael's Cajun Seafood & Wings is a vibrant and inviting restaurant located at 5054 Old Buncombe Road in Greenville, South Carolina. Specializing in Cajun cuisine, this establishment offers a mouthwatering selection of seafood and wings that will tantalize your taste buds. With a cozy atmosphere and friendly staff, Michael's is the perfect spot to enjoy a delicious meal with family and friends. Whether you're craving spicy shrimp gumbo, crispy fried catfish, or flavorful Cajun wings, this restaurant has something for everyone. Come experience the bold flavors and Southern hospitality that Michael's Cajun Seafood & Wings has to offer.

Angus Steakhouse and Seafood is a premier dining destination located at 2011 South Kings Highway in Myrtle Beach, South Carolina. Our restaurant offers a unique culinary experience, specializing in high-quality cuts of Angus beef and fresh seafood dishes. With a cozy and inviting atmosphere, guests can enjoy a delectable meal while taking in the beautiful surroundings of Myrtle Beach. Whether you're craving a juicy steak or a succulent seafood platter, Angus Steakhouse and Seafood is the perfect spot for a memorable dining experience.

Blu Oyster Sushi & Seafood is a top-notch restaurant located at 1804 Crowne Commons Way in Johns Island, South Carolina. Specializing in fresh local seafood and high-quality sushi, this establishment is the perfect spot for any occasion. Whether you're celebrating a birthday, hosting an office function, or planning a bridal shower, Blu Oyster has you covered. Their attentive staff will ensure that your event is a success, leaving you free to enjoy the festivities. With a diverse menu and a great selection of dishes, including oyster hash and a Bloody Mary bar, this restaurant is a must-visit for seafood lovers. The cozy atmosphere, friendly service, and delicious food make Blu Oyster Sushi & Seafood a standout dining destination in Johns Island. Book your table today and experience the best of local seafood and sushi in South Carolina!

Grumpy Goat Seafood Cantina is a charming restaurant located at 1023 Harbor View Road in Charleston, South Carolina. Specializing in fresh seafood dishes, this cozy cantina offers a unique dining experience with a laid-back atmosphere. From succulent shrimp tacos to mouthwatering crab cakes, the menu features a variety of delicious options for seafood lovers. With its friendly staff and inviting ambiance, Grumpy Goat Seafood Cantina is the perfect spot to enjoy a satisfying meal in the heart of Charleston.

Puerto Nuevo Mexican & Seafood Restaurant is a vibrant dining establishment located at 105 Interstate Boulevard in Anderson, South Carolina. Specializing in delicious Mexican and seafood cuisine, this restaurant offers a diverse menu filled with mouthwatering dishes that will tantalize your taste buds. Whether you're in the mood for traditional Mexican favorites like tacos and enchiladas or fresh seafood options like shrimp cocktails and ceviche, Puerto Nuevo has something for everyone. The inviting atmosphere and friendly staff make this restaurant the perfect spot for a casual meal with friends or a special celebration with loved ones. Come experience the flavors of Mexico and the sea at Puerto Nuevo Mexican & Seafood Restaurant.

Blue Ocean Seafood Restaurant is a charming dining destination located in Clinton, South Carolina. Situated at 12763 South Carolina 56, this restaurant offers a wide variety of fresh and delicious seafood dishes that will tantalize your taste buds. Whether you're craving succulent crab legs, flavorful shrimp scampi, or a hearty seafood platter, Blue Ocean has something for everyone. With a cozy atmosphere and friendly staff, this restaurant is the perfect place to enjoy a memorable dining experience with friends and family. Come visit Blue Ocean Seafood Restaurant and dive into a culinary adventure unlike any other.

Palmetto Seafood Bar and Grill is a charming restaurant located at 158 Lee Street in Johnston, South Carolina. This cozy establishment offers a wide variety of delicious seafood dishes, grilled to perfection. From fresh oysters to succulent shrimp and mouthwatering crab cakes, Palmetto Seafood Bar and Grill is sure to satisfy your seafood cravings. The welcoming atmosphere and friendly staff make it the perfect spot for a casual meal with family and friends. Come and experience the taste of the sea at Palmetto Seafood Bar and Grill.

Fiddlers Seafood Restaurant, located at 7738 West Main Street in Ridgeland, South Carolina, is a charming and historic establishment known for its fresh seafood and homemade dishes. With a motto of "From Our Boat, to Your Table," Fiddlers prides itself on serving the freshest catch of the day in a welcoming and cozy atmosphere. Whether you're craving a classic seafood dish or one of their signature homemade specialties, Fiddlers Seafood Restaurant is sure to delight your taste buds and leave you satisfied. Come experience a true taste of the Lowcountry at this beloved seafood destination.

Seafood Pot is a popular restaurant located at 5629 Rivers Avenue in North Charleston, South Carolina. This cozy eatery specializes in serving up delicious seafood dishes that are sure to satisfy your cravings. From succulent shrimp and crab legs to flavorful fish and oysters, Seafood Pot offers a wide variety of options to choose from. Whether you're in the mood for a hearty seafood boil or a light and refreshing salad, this restaurant has something for everyone. Come dine at Seafood Pot and experience the fresh flavors of the sea in a welcoming and inviting atmosphere.

Located at 1734 Sam Rittenberg Boulevard in Charleston, South Carolina, King Claw - Juicy Seafood & Bar is a premier seafood boil restaurant that promises an exceptional dining experience for seafood enthusiasts. Specializing in a wide range of seafood options such as crab legs, shrimp, and crawfish, all cooked to perfection in their signature Cajun-style King Claw seasoning, this restaurant is committed to providing the freshest and highest quality seafood sourced locally and prepared daily by expert chefs. The vibrant and fun atmosphere of King Claw celebrates the oceanic world with unique decor, making it the perfect spot to enjoy a delicious seafood meal. The restaurant prides itself on exceptional customer service, focusing on friendly service and attention to detail to ensure a memorable dining experience for every guest.

NICO | Oysters Seafood is a charming restaurant located at 201 Coleman Boulevard in Mount Pleasant, South Carolina. Specializing in fresh oysters and seafood, this establishment offers a delightful dining experience with a focus on high-quality ingredients and exceptional service. Guests can enjoy a variety of seafood dishes prepared with a creative twist, as well as a selection of delicious oysters sourced from local waters. The cozy atmosphere and waterfront location make NICO | Oysters Seafood the perfect spot for a memorable meal with friends and family.

B-Doe's Seafood & More Located at 2500 Winchester Pl #108 in Spartanburg, South Carolina, B-Doe's Seafood & More is a culinary gem that offers a delightful dining experience for seafood enthusiasts and food lovers alike. Specializing in a wide array of fresh and flavorful seafood dishes, this local restaurant prides itself on delivering high-quality meals that capture the essence of coastal cuisine.

Welcome to The Quay Seafood Grille, your premier dining destination in the heart of Murrells Inlet, South Carolina! Nestled at 1508 S Waccamaw Dr, our restaurant offers an unforgettable culinary experience with stunning waterfront views. Specializing in fresh, locally-sourced seafood, our menu features a wide array of delectable dishes crafted to delight your taste buds. Whether you're craving classic low-country favorites or innovative seafood creations, our talented chefs are dedicated to serving you the finest flavors the sea has to offer. At The Quay Seafood Grille, we pride ourselves on providing exceptional service in a warm and inviting atmosphere. Perfect for family gatherings, romantic dinners, or casual outings with friends, our restaurant is the ideal spot to savor a delicious meal while enjoying the serene beauty of Murrells Inlet. Join us for a memorable dining experience where the freshest catches of the day meet Southern hospitality. We look forward to welcoming you soon!

Street Tacos and Seafood is a vibrant and bustling restaurant located at 102 West Main Street in Pickens, South Carolina. Specializing in delicious street-style tacos and fresh seafood dishes, this establishment offers a unique and flavorful dining experience for locals and visitors alike. From savory shrimp tacos to mouthwatering ceviche, guests can enjoy a diverse menu of Mexican and seafood-inspired cuisine. The welcoming atmosphere and friendly service make Street Tacos and Seafood a must-visit destination for those looking to satisfy their cravings for authentic and tasty dishes.

Seabrisa's Waterfront Seafood Restaurant is a charming dining establishment located at 4498 Water Front Avenue in Little River, South Carolina. This restaurant is a hidden gem offering a delightful culinary experience with a focus on fresh seafood. Situated right on the waterfront, guests can enjoy picturesque views while savoring delicious dishes made with the finest ingredients. The inviting atmosphere and friendly staff make Seabrisa's a perfect choice for a memorable meal with family and friends. Whether you're a seafood enthusiast or simply looking for a great dining experience, Seabrisa's Waterfront Seafood Restaurant is sure to leave a lasting impression.

Sushi King Steak & Seafood is a popular dining destination located at 4036 River Oaks Drive in Myrtle Beach, South Carolina. This restaurant offers a unique blend of traditional Japanese cuisine and American steakhouse favorites. Guests can enjoy a wide variety of freshly prepared sushi rolls, sashimi, and nigiri, as well as premium cuts of steak and fresh seafood dishes. The elegant atmosphere and attentive service make Sushi King Steak & Seafood the perfect spot for a special night out or a casual meal with friends and family.

Puerto Nuevo Mexican & Seafood Restaurant is a vibrant and welcoming establishment located in West Union, South Carolina. Situated at 201 Foothills Center Drive, this restaurant offers a unique blend of Mexican and seafood cuisine that is sure to delight your taste buds. Whether you're in the mood for sizzling fajitas, fresh seafood dishes, or a refreshing margarita, Puerto Nuevo has something for everyone. With a lively atmosphere and attentive staff, this restaurant is the perfect place to gather with friends and family for a delicious meal. Come experience the flavors of Mexico and the sea at Puerto Nuevo Mexican & Seafood Restaurant.

Miyabi Japanese Steak & Seafood House is a popular dining destination located at 625 Congaree Road in Greenville, South Carolina. This restaurant offers a unique and interactive dining experience, where skilled chefs prepare delicious Japanese cuisine right before your eyes on a teppanyaki grill. From sizzling steak and seafood to fresh vegetables and rice, Miyabi offers a wide variety of options to satisfy your cravings. The vibrant atmosphere, friendly staff, and exceptional food make Miyabi Japanese Steak & Seafood House a must-visit for anyone looking for a memorable dining experience in Greenville.

Silver Bay Seafood Restaurant is a charming dining establishment located at 6513 White Horse Road in Greenville, South Carolina. Specializing in fresh seafood dishes, this restaurant offers a diverse menu filled with delicious options such as shrimp, crab, oysters, and fish. The cozy atmosphere and friendly staff make it the perfect spot for a casual meal or a special occasion. Whether you're a seafood lover or just looking to try something new, Silver Bay Seafood Restaurant is sure to leave you satisfied and coming back for more.

Williams Seafood is a popular food and meal takeaway restaurant located in Walterboro, South Carolina. Situated at 100 State Road S-15-78, this institution is known for its delicious seafood dishes that are freshly prepared and bursting with flavor. Whether you're craving fried shrimp, crab cakes, or a seafood platter, Williams Seafood has something for everyone. With a welcoming atmosphere and friendly staff, this restaurant is the perfect spot to enjoy a tasty meal with family and friends.

Gillie's Seafood is a charming restaurant located at 805 Folly Road in Charleston, South Carolina. Known for its fresh and delicious seafood dishes, Gillie's offers a diverse menu featuring a variety of seafood options such as shrimp, oysters, crab, and fish. With a cozy and inviting atmosphere, Gillie's is the perfect spot to enjoy a meal with family and friends while taking in the beautiful surroundings of Charleston. Whether you're craving a classic shrimp boil or a mouthwatering seafood pasta, Gillie's Seafood is sure to satisfy your seafood cravings.

The Seafood Spot is a popular restaurant located at 219 West Antrim Drive in Greenville, South Carolina. Specializing in fresh and delicious seafood dishes, this spot is a go-to destination for seafood lovers in the area. With a cozy atmosphere and friendly staff, diners can enjoy a variety of seafood options including shrimp, crab, lobster, and more. Whether you're craving a classic seafood boil or a gourmet seafood pasta dish, The Seafood Spot has something for everyone. Come and experience the flavors of the sea at this fantastic dining establishment.

Located in the heart of the French Quarter in downtown Charleston, South Carolina, the Oyster House Seafood Restaurant is a popular spot for both locals and visitors. With a menu featuring fresh seafood and Lowcountry favorites, such as oysters on the half shell and shrimp & grits, this restaurant offers a taste of the region's culinary heritage. The historical ambiance of the restaurant, with its exposed brick walls and original wooden beams, adds to the charm of the dining experience. Whether you choose to dine on the patio overlooking the Charleston Market or inside the restaurant, you can enjoy a variety of dishes such as crab and avocado toast, garlic mussels, and fire-roasted oysters. In addition to seafood options, the restaurant also offers salads, sandwiches, and entrees like roasted chicken and seafood casserole. With a wide range of dishes to choose from, the Oyster House Seafood Restaurant is the perfect place to enjoy a meal in Charleston.

Lawrence's Seafood Company is a charming restaurant located at 1130 Ocean Boulevard in the beautiful Isle of Palms, South Carolina. Specializing in fresh and delicious seafood dishes, this establishment offers a variety of options to satisfy any seafood lover's cravings. From succulent shrimp and crab to mouthwatering fish dishes, Lawrence's Seafood Company is the perfect place to enjoy a taste of the ocean while taking in the stunning views of the nearby beach. Whether you're looking for a casual meal with family and friends or a romantic dinner for two, Lawrence's Seafood Company is sure to provide a memorable dining experience.

Big E's Country Buffet & Seafood is a popular dining destination located in Longs, South Carolina. This welcoming restaurant offers a wide variety of delicious Southern comfort food and fresh seafood dishes. Guests can enjoy an all-you-can-eat buffet featuring homestyle favorites like fried chicken, mashed potatoes, and collard greens, as well as a selection of freshly prepared seafood options. The casual and inviting atmosphere makes it the perfect spot for a family meal or gathering with friends. With its convenient location on South Carolina Highway 9, Big E's Country Buffet & Seafood is a must-visit for anyone looking for a satisfying and hearty dining experience in the area.