TOP 30 Best Hotel for road trips in South Carolina

Holiday Inn Express & Suites Greenville SE - Simpsonville is a modern and comfortable lodging option located at 642 Fairview Road in Simpsonville, South Carolina. As an IHG Hotel, guests can expect top-notch service and amenities during their stay. The hotel offers spacious and well-appointed rooms and suites, along with a complimentary breakfast buffet to start the day off right. Guests can also enjoy the indoor pool, fitness center, and business center during their stay. With its convenient location and excellent facilities, Holiday Inn Express & Suites Greenville SE - Simpsonville is the perfect choice for both business and leisure travelers visiting the area.

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 is a modern and comfortable lodging option located in Florence, South Carolina. Situated conveniently off of Highway 327, this IHG hotel offers a range of amenities and services to ensure a pleasant stay for guests. The spacious rooms and suites are tastefully decorated and equipped with all the necessary facilities for a relaxing stay. Guests can enjoy complimentary breakfast, access to the fitness center, and a refreshing indoor pool. The hotel's convenient location provides easy access to nearby attractions and dining options. Whether traveling for business or leisure, Holiday Inn Express & Suites Florence I-95 @ Hwy 327 is a great choice for a comfortable and enjoyable stay in South Carolina.

The Hampton Inn Greenville I-385 - Woodruff Road is a comfortable and convenient lodging option located at 15 Park Woodruff Drive in Greenville, South Carolina. This well-appointed hotel offers spacious rooms, modern amenities, and a friendly staff to ensure a pleasant stay for guests. Situated near the bustling Woodruff Road area, guests can easily access shopping, dining, and entertainment options. Whether visiting for business or leisure, the Hampton Inn Greenville I-385 - Woodruff Road provides a relaxing retreat in the heart of Greenville.

Tru by Hilton Greenville Woodruff Road is a modern and stylish lodging option located at 122 Carolina Point Parkway in Greenville, South Carolina. This vibrant hotel offers a unique and fun experience for guests, with a focus on simplicity, comfort, and technology. The hotel is conveniently situated near the bustling Woodruff Road area, providing easy access to shopping, dining, and entertainment options. Guests can enjoy amenities such as a fitness center, complimentary breakfast, and a lively lobby area perfect for socializing or relaxing. Whether you're traveling for business or leisure, Tru by Hilton Greenville Woodruff Road is the perfect choice for a comfortable and enjoyable stay.

Holiday Inn Express Charleston US Hwy 17 & I-526 is a comfortable and convenient lodging option located in Charleston, South Carolina. Situated at 1943 Savannah Highway, this IHG Hotel offers easy access to both the highway and the city's attractions. The hotel provides a range of amenities including complimentary breakfast, free Wi-Fi, a fitness center, and a seasonal outdoor pool. The rooms are spacious and well-appointed, ensuring a relaxing stay for guests. Whether visiting for business or pleasure, Holiday Inn Express Charleston US Hwy 17 & I-526 is a great choice for travelers looking for a comfortable and affordable accommodation option in Charleston.

Holiday Inn Express Anderson-I-85 (Exit 27-Hwy 81), an IHG Hotel, is a comfortable and convenient lodging option located at 410 Alliance Parkway in Anderson, South Carolina, United States. This hotel offers modern amenities and spacious rooms for guests to relax and unwind during their stay. With easy access to Interstate 85 and Highway 81, it is the perfect choice for travelers passing through or visiting the Anderson area. Guests can enjoy complimentary breakfast, free Wi-Fi, a fitness center, and a business center. The hotel's friendly staff is dedicated to providing excellent service to ensure a pleasant stay for all guests.

Welcome to avid hotel Fort Mill - Amusement Park, an IHG Hotel! Located at 154 Springhill Farm Road in Fort Mill, South Carolina, our modern and stylish lodging option is perfect for guests looking to explore the nearby amusement park attractions. Our hotel offers comfortable and well-appointed rooms, designed with the avid traveler in mind. Enjoy amenities such as free WiFi, a 24-hour fitness center, and a complimentary breakfast to start your day off right.

SPS Tranquility for Travelers is a unique institution located at 307 Hamburg Road in Easley, South Carolina. As a combination of lodging, real estate agency, and travel agency, SPS Tranquility for Travelers offers a one-stop solution for all your travel needs. Whether you are looking for a cozy place to stay, interested in buying or renting a property, or planning your next vacation, our experienced team is here to help. With a focus on providing a tranquil and stress-free experience for all travelers, SPS Tranquility for Travelers is your go-to destination for all things travel-related in Easley, South Carolina.

Holiday Inn Greenville - Woodruff Road is a welcoming and comfortable lodging option located at 25 Old Country Road in Greenville, South Carolina. As an IHG Hotel, guests can expect top-notch service and amenities during their stay. The hotel is conveniently situated near the bustling Woodruff Road area, offering easy access to shopping, dining, and entertainment options. Whether you're visiting for business or leisure, Holiday Inn Greenville - Woodruff Road provides a relaxing retreat with spacious rooms, a fitness center, on-site dining options, and a friendly staff ready to make your stay memorable.

Holiday Inn & Suites Beaufort @ Highway 21, an IHG Hotel, is a welcoming and modern lodging option located in Beaufort, South Carolina. Situated on Boundary Street, this hotel offers comfortable rooms and suites for guests looking to explore the charming city and its surroundings. With convenient access to Highway 21, visitors can easily reach local attractions, restaurants, and shopping centers. The hotel boasts a range of amenities, including a fitness center, outdoor pool, and on-site restaurant, making it a great choice for both leisure and business travelers. Whether you are visiting for a weekend getaway or an extended stay, Holiday Inn & Suites Beaufort provides a cozy and convenient home away from home.

108 Lighthouse Road is a reputable institution located in the heart of Hilton Head Island, South Carolina. As a dual-functioning establishment, it serves as both a real estate agency and a travel agency, catering to the needs of both locals and tourists alike. Whether you are looking to buy or sell property in this beautiful coastal town, or seeking assistance in planning your next vacation to Hilton Head Island, 108 Lighthouse Road has the expertise and resources to help you every step of the way. With a prime location and a team of knowledgeable professionals, this institution is your go-to destination for all things real estate and travel-related on the island. Visit 108 Lighthouse Road today and let them guide you towards your next adventure.

Hi C Farms and Kennels LLC is a unique travel agency located at 2775 Ranger Road in Clover, South Carolina, United States. Our institution specializes in providing personalized travel experiences for pet owners who want to bring their furry friends along on their adventures. We offer a range of services including pet-friendly accommodations, transportation, and activities to ensure that both you and your pet have a memorable and stress-free trip. With our team of experienced professionals, you can rest assured that your pet will be well taken care of while you explore new destinations. Contact us today to start planning your next pet-friendly vacation!

Cross Island Bike Rental is a premier bicycle store located at 13 Executive Park Road in Hilton Head Island, South Carolina. We offer a wide selection of high-quality bicycles for rent, perfect for exploring the beautiful island and its scenic surroundings. Whether you're looking for a leisurely ride along the beach or a challenging mountain biking adventure, we have the perfect bike for you. Our knowledgeable staff is dedicated to providing excellent customer service and ensuring that you have a memorable biking experience. Visit us today and start your island adventure with Cross Island Bike Rental.

Solitude Pointe Cabins and RV Park is a peaceful retreat nestled in the scenic beauty of Cleveland, South Carolina. Located at 102 Table Rock Road, this institution offers a range of accommodation options including cozy cabins and spacious RV sites. Whether you're looking for a weekend getaway or a longer stay, Solitude Pointe provides a tranquil escape from the hustle and bustle of everyday life. With its convenient location and well-maintained facilities, this institution is perfect for nature lovers, outdoor enthusiasts, and anyone seeking a relaxing vacation. Book your stay at Solitude Pointe Cabins and RV Park through their real estate and travel agency services for a memorable experience in the heart of the United States.

Bulls Island Ferry is a popular travel agency located at 498 Bulls Island Road in Awendaw, South Carolina. This institution offers ferry services to Bulls Island, a beautiful park known for its pristine beaches, diverse wildlife, and stunning landscapes. Visitors can enjoy a scenic boat ride across the water to reach this hidden gem and explore all that it has to offer. Whether you're looking for a relaxing day in nature or an adventure-filled excursion, Bulls Island Ferry is the perfect starting point for your journey.

Pine Ridge Campground is a serene and picturesque retreat located at 199 Pineridge Campground Road in Roebuck, South Carolina, United States. This charming institution offers a variety of accommodations including camping sites, lodging options, and RV parks. Guests can enjoy the beauty of nature while fishing at the one-acre pond on the campground grounds. For those looking to relax and unwind, there is a cozy white shed selling firewood with a hand-painted sign featuring a campfire motif.

All Seasons Family Campground is a peaceful retreat nestled in the heart of Cross Hill, South Carolina. Situated at 2075 Watts Bridge Road, this charming campground offers a variety of lodging options for families looking to escape the hustle and bustle of city life. Surrounded by lush greenery and towering trees, All Seasons Family Campground provides a serene setting for guests to relax and unwind. The park-like grounds feature spacious RV sites, cozy cabins, and tent camping areas, ensuring there is something for every type of camper.

Home2 Suites by Hilton Duncan is a modern and comfortable lodging facility located at 104 Spartangreen Boulevard in Duncan, South Carolina. This hotel offers spacious suites with fully equipped kitchens, free Wi-Fi, and a complimentary breakfast buffet. Guests can also enjoy amenities such as a fitness center, outdoor pool, and a business center. The convenient location near major highways makes it easy to explore the surrounding area and nearby attractions. Whether you're traveling for business or leisure, Home2 Suites by Hilton Duncan provides a welcoming and relaxing stay for all guests.

Dreher Island State Park, located at 3677 State Park Road in Prosperity, South Carolina, is a beautiful park and tourist attraction. Visitors can enjoy camping, fishing, hiking, and other outdoor activities in this scenic location. The park offers various accommodations including camper cabins and villas, with check-in at the Tackle Shop. Admission to the park is $3 for adults, $1.50 for South Carolina seniors, and $1 for children aged 6-15. Children under 5 enter for free. Beginning January 1, 2020, pets will be allowed in camper cabins 2-5, but not in the villas or villa areas. Pets must be kept on a leash and under control in most outdoor areas.

Oconee Point Campground is a beautiful institution located at 200 Oconee Point Road in Seneca, South Carolina, United States. This campground offers a variety of lodging options and is the perfect place for outdoor enthusiasts to enjoy the natural beauty of the area. At Oconee Point Campground, visitors can explore over 3,600 facilities and 103,000 individual sites across the country through Recreation.gov. Whether you enjoy camping, hiking, horseback riding, wildlife viewing, or ranger-led activities, there is something for everyone to experience.

Charleston Kiawah Island/Andell Inn is a luxurious lodging facility located at 300 Farm Lake View Road in the picturesque Kiawah Island, South Carolina. This upscale inn offers guests a tranquil and relaxing retreat surrounded by the natural beauty of the Lowcountry. The modern amenities and elegant decor of the Andell Inn provide a comfortable and inviting atmosphere for guests to enjoy during their stay. Whether you are looking for a romantic getaway, a family vacation, or a business trip, Charleston Kiawah Island/Andell Inn offers the perfect blend of comfort and sophistication. Experience the charm and hospitality of the South at this exceptional lodging destination.

Seawatch at Island Club is a charming lodging institution located at 85 Folly Field Road in Hilton Head Island, South Carolina, United States. Nestled in a picturesque coastal setting, this establishment offers guests a peaceful retreat with easy access to the island's beautiful beaches and attractions. The accommodations at Seawatch at Island Club are cozy and well-appointed, providing guests with a comfortable stay during their visit. Whether you're looking for a relaxing getaway or a fun-filled vacation, this institution is the perfect choice for your stay on Hilton Head Island.

Hilton Head Guest Services is a premier travel agency located at 1 Executive Park Road on the beautiful Hilton Head Island in South Carolina, United States. Our experienced team is dedicated to providing exceptional service to our guests, ensuring they have an unforgettable experience during their visit to this stunning destination. Whether you are looking for assistance with accommodations, activities, or local attractions, Hilton Head Guest Services is here to help make your trip truly memorable. Visit us today and let us take care of all your travel needs.

Located at 20 Puckett Ferry Road in Cross Hill, South Carolina, Liberty Springs RV Park is a serene and picturesque campground offering lodging for RV enthusiasts. Nestled in the heart of nature, this park provides a peaceful retreat for those looking to escape the hustle and bustle of everyday life. With spacious RV sites, modern amenities, and beautiful surroundings, guests can enjoy a relaxing stay surrounded by the beauty of South Carolina. Whether you're looking to explore the nearby attractions or simply unwind in nature, Liberty Springs RV Park is the perfect destination for your next getaway.

Lake Murray Boat Rentals is a premier watercraft rental service located at 960 Rock North Creek Road in South Carolina, United States. Nestled on the picturesque Lake Murray, our institution offers a wide variety of boats for rent, including pontoons, jet skis, and fishing boats. Whether you're looking for a relaxing day on the water or an exhilarating adventure, our rentals are perfect for individuals, families, and groups alike. Our knowledgeable staff is dedicated to providing top-notch customer service and ensuring a safe and enjoyable experience for all. Come visit Lake Murray Boat Rentals and make unforgettable memories on the water.

The Hampton Inn & Suites Walterboro is a comfortable and convenient lodging option located at 129 Cane Branch Road in Walterboro, South Carolina. This modern hotel offers a range of amenities including spacious rooms and suites, complimentary breakfast, a fitness center, and an outdoor pool. Whether you are traveling for business or leisure, the Hampton Inn & Suites Walterboro provides a relaxing and enjoyable stay for guests. With its convenient location and excellent service, this hotel is the perfect choice for your next trip to the charming town of Walterboro.

Port O' Call Resort by Palmera is a charming lodging option located at 13 Barcelona Road in Hilton Head Island, South Carolina. This cozy resort offers comfortable accommodations and a relaxing atmosphere for guests to enjoy during their stay. Whether you're looking for a weekend getaway or a longer vacation, Port O' Call Resort by Palmera is the perfect choice for your next trip to Hilton Head Island. With its convenient location and welcoming hospitality, this resort is sure to provide a memorable experience for all guests.

Welcome to Vivo Living Port Royal, located at 1660 Ribaut Road in Port Royal, South Carolina, United States. Our community offers a friendly and convenient environment for those seeking a quaint lifestyle. Our apartment homes are designed to cater to your needs and come equipped with a variety of features and amenities to make your daily routine easier. Whether you're looking to relax or stay active, our community has everything you need. Enjoy our sparkling swimming pool, state-of-the-art fitness center, and cozy clubhouse for socializing with friends. We also offer online rent payments, 24-hour maintenance, and package receiving for your convenience.

Tru by Hilton Rock Hill is a modern and stylish lodging option located at 800 Galleria Boulevard in Rock Hill, South Carolina. This vibrant hotel offers comfortable and contemporary accommodations for travelers looking for a convenient and enjoyable stay. With a focus on simplicity, affordability, and connectivity, Tru by Hilton Rock Hill provides guests with a refreshing and welcoming atmosphere. Amenities include free WiFi, a fitness center, complimentary breakfast, and a 24/7 market. Whether you're visiting for business or leisure, Tru by Hilton Rock Hill is the perfect choice for your stay in South Carolina.

Nestled in the heart of Myrtle Beach, South Carolina, Apache Family Campground & Pier offers a serene escape for families and outdoor enthusiasts. Our campground features spacious RV sites, cozy cabins, and tent camping options, all surrounded by lush greenery and just steps away from the pristine shores of the Atlantic Ocean. The highlight of our facility is the iconic Apache Pier, the East Coast's longest wooden fishing pier, where visitors can cast a line, take in stunning ocean views, or simply relax and unwind. With amenities such as a playground, swimming pool, and picnic areas, Apache Family Campground & Pier is the perfect destination for a fun-filled and memorable vacation in Myrtle Beach.