The 30 Best Unique accommodations in San Diego, California

The Lafayette Hotel is a historic and charming lodging establishment located at 2223 El Cajon Boulevard in San Diego, California, United States. This iconic hotel offers a unique blend of retro style and modern amenities, providing guests with a comfortable and memorable stay. With its convenient location near popular attractions, restaurants, and shopping destinations, The Lafayette Hotel is the perfect choice for travelers looking to experience the vibrant culture of San Diego. Whether you are visiting for business or leisure, you will be welcomed with exceptional service and a welcoming atmosphere at The Lafayette Hotel.

ITH CoLive Little Italy Hostel is a charming lodging establishment located in the heart of San Diego's vibrant Little Italy neighborhood. Situated at 1658 Front Street, this hostel offers budget-friendly accommodations in a convenient location near popular attractions, restaurants, and shops. The hostel provides comfortable dormitory-style rooms and private rooms, perfect for solo travelers, families, and groups. Guests can enjoy a communal kitchen, lounge area, and outdoor patio. With its friendly staff and cozy atmosphere, ITH CoLive Little Italy Hostel is the ideal choice for travelers looking for a unique and affordable stay in San Diego.

Welcome to Harborview Inn and Suites, your ideal San Diego getaway located at 550 West Grape Street. Our hotel is just minutes away from the San Diego International Airport and within walking distance to museums, entertainment venues, and unique shops. Situated near Little Italy, our 100% smoke-free hotel offers a friendly 24-hour front desk staff, concierge service, and complimentary coffee and tea in the lobby. Guests can enjoy amenities such as complimentary on-site parking, a 24-hour business center, and daily housekeeping services. Our multi-lingual staff is dedicated to ensuring a comfortable and convenient stay for all guests. San Diego is known for its beautiful beaches, art culture, and world-class attractions, all of which are easily accessible from Harborview Inn and Suites. Whether you're interested in exploring the Gaslamp District, visiting the San Diego Zoo, or enjoying a game at Petco Park, our hotel puts you in the heart of all the action. With our accessible private bathrooms and amenities like auditory guidance and tactile signs, we strive to make every guest feel welcome and at home during their stay. Book your San Diego getaway with us today and experience all that this vibrant city has to offer.

Abpópa Hillcrest is a unique micro loft boutique lodging located in the vibrant neighborhood of Hillcrest in San Diego, California. Situated at 3776 Fourth Avenue, this lodging offers small studios with living rooms, mini kitchens, and split level floor plans. The design of the micro lofts provides a cozy and comfortable atmosphere for guests to enjoy their stay. Named in honor of the famed Russian cruiser launched in 1900, Abpópa Hillcrest is surrounded by must-see attractions, eateries, events, and natural beauty in every direction. The location in Hillcrest puts guests at the cultural and geographical heart of San Diego, offering convenient access to everything the city has to offer.

Welcome to Ciao Boutique Hotel Mission Valley, where the charm and elegance of Italy meet the vibrant city of San Diego. Our boutique hotel offers a unique blend of sophisticated accommodation and a prime location, all inspired by the romance and beauty of Italy. Whether you're a family looking for spacious suites or a couple seeking a cozy retreat, Ciao Boutique Hotel Mission Valley is your Italian-inspired home away from home. Immerse yourself in the ambiance of Italy with our thoughtfully designed suites, each inspired by iconic Italian destinations such as Tuscany, Rome, and Positano. Our suites feature full kitchens for you to cook up your favorite Italian dishes, as well as a laundry room to keep your clothes fresh for your adventures. Whether you choose a 2-bedroom or 4-bedroom suite, you'll find spacious and well-appointed accommodations that transport you to the heart of Italy.

The Horton Grand Hotel is a charming historic lodging located at 311 Island Avenue in the heart of San Diego, California. This elegant hotel offers a unique blend of Victorian architecture and modern amenities, providing guests with a comfortable and unforgettable stay. With its central location, guests can easily explore the nearby attractions such as the Gaslamp Quarter, Petco Park, and the San Diego Convention Center. The Horton Grand Hotel is the perfect choice for travelers looking for a cozy and stylish accommodation in San Diego.

Kimpton Alma is a stylish and modern lodging institution located at 1047 Fifth Avenue in San Diego, California. Situated near the historic Gaslamp District and Little Italy, our hotel offers a unique blend of Southern California cool and Mexican heritage. Our lobby pays homage to the rich cultural influences that shape our city's laid-back vibe. Guests can enjoy the vibrant atmosphere of our outdoor pool and destination restaurants, including The Desmond, a fine-dining restaurant that offers a memorable culinary experience. By booking direct on our website and becoming an IHG® One Rewards member, guests can access exclusive benefits and earn points at over 6,000 destinations worldwide.

Located at 2502 Washington Street in Julian, California, Orchard Hill is a premier boutique hotel offering a unique blend of rustic charm and modern comfort. Nestled in the San Diego mountains, this lodging institution provides a curated experience for guests looking for an adventure-filled stay. The crisp mountain air and panoramic views set the stage for an unforgettable retreat, ideal for those seeking a peaceful getaway or an adventurous excursion in Downtown Julian. Orchard Hill offers a range of activities, from horseback riding tours through scenic mountain trails to expert-led e-bike tours exploring hidden gems and breathtaking views. Guests can also indulge in blissful yoga sessions, soothing massage therapies, and farm-to-table dining experiences featuring locally sourced ingredients.

Skyfari is an aerial tram located at the San Diego Zoo in California, United States, offering guests a unique and scenic way to travel from one end of the zoo to the other. Enjoy breathtaking views of the zoo and surrounding Balboa Park as you soar above the treetops. Guests are welcome to bring folded strollers on the Skyfari Aerial Tram, as long as they do not exceed 23 inches at their widest point. Stroller size will be assessed by team members before boarding at each station, and stroller parking is available near the entrance of both Skyfari East and Skyfari West stations. Please remember to remove personal items from strollers and take valuable belongings with you to prevent theft.

Safari Base Camp is an immersive wildlife experience located at 15500 San Pasqual Valley Road in Escondido, California. Visitors can embark on a thrilling adventure through the stunning landscapes and diverse habitats of the United States. The camp offers a unique opportunity to observe and interact with a variety of exotic animals in a safe and educational environment. From guided safaris to hands-on encounters, Safari Base Camp provides an unforgettable experience for nature enthusiasts of all ages. Join us for an unforgettable journey into the wild!

Orfila Vineyards and Winery is a must-visit destination located at 13455 San Pasqual Road in Escondido, California. This beautiful institution offers a unique experience for food and wine enthusiasts, as well as tourists looking to explore the San Diego County wine region. Guests are invited to join the Orfila Wine Lovers (OWL) Club, which provides a 20% discount on wine and merchandise purchases. Visitors can enjoy daily tours of the vineyards, where they can learn about the different varietals grown on the estate and the winemaking process.

The Windsor Hotel is a charming and historic lodging establishment located at 843 Fourth Avenue in the heart of San Diego, California. This beautifully appointed hotel offers a perfect blend of modern amenities and old-world charm, making it a favorite choice for travelers seeking a comfortable and memorable stay. The Windsor Hotel boasts elegantly decorated rooms, a friendly and attentive staff, and convenient access to the city's top attractions, restaurants, and shops. Whether you are visiting San Diego for business or pleasure, the Windsor Hotel is the perfect place to relax and unwind during your stay in sunny California.

Madison Hospitality is a premier lodging institution located in the heart of San Diego, California, United States. With a reputation for exceptional service and luxurious accommodations, Madison Hospitality offers a unique and unforgettable experience for guests. Whether you are traveling for business or pleasure, our convenient location and top-notch amenities make us the perfect choice for your stay in San Diego. Come experience the comfort and hospitality of Madison Hospitality during your next visit to this vibrant city.

El Cortez Hill is a charming lodging institution located at 818 Sixth Avenue in the heart of San Diego, California. This historic building offers a unique stay experience with its cozy accommodations and convenient location. Guests can enjoy comfortable rooms, friendly service, and easy access to the city's attractions, dining, and entertainment options. Whether you're visiting for business or leisure, El Cortez Hill provides a welcoming and relaxing atmosphere for your stay in San Diego.

THE GREELY by Casa Mayra Collection is a luxurious lodging institution located at 825 Fifth Avenue in the vibrant city of San Diego, California, United States. This elegant establishment offers a unique and sophisticated stay experience, with beautifully designed rooms and top-notch amenities. Guests can enjoy impeccable service, stunning views, and a prime location near some of the city's most popular attractions. Whether visiting for business or pleasure, THE GREELY provides a tranquil and upscale retreat for discerning travelers.

Old Town is a charming lodging institution located at 2254 Moore Street in the heart of San Diego, California. This historic property offers guests a unique and authentic experience in the bustling Old Town district. The rooms are beautifully decorated with a blend of modern amenities and traditional charm. Guests can enjoy the convenience of being within walking distance to shops, restaurants, and attractions. Whether you are visiting for business or pleasure, Old Town provides a comfortable and welcoming atmosphere for all travelers.

Cyrus Travel is a renowned travel agency located at 1190 South Bascom Avenue in San Jose, California, United States. We believe that every trip is special and strive to provide great deals for unforgettable tours. Our agency offers free shuttle services from Sacramento to San Francisco and from San Diego to Los Angeles, making your travel experience even more convenient. We recently received glowing reviews from clients who traveled to Iran, praising our knowledgeable guides and excellent accommodations. With over 57 years of experience, Cyrus Travel is known as the premier source for travel to Iran and Europe among the 1.5 million Iranian nationals living in the United States. Our agency is dedicated to providing outstanding, value-added services to all our customers.

Cyrus Travel is a renowned travel agency located at 9454 Wilshire Boulevard, Beverly Hills, California, United States. Every trip booked with Cyrus Travel is a special experience, with great deals and unforgettable tours. The agency offers free shuttle services to/from Sacramento to San Francisco and San Diego to Los Angeles, making travel convenient for all clients. Recent travelers have raved about their amazing trips to Iran, with excellent guides and top-notch accommodations. Cyrus Travel is highly recommended by the 1.5 million Iranian nationals living in the United States for its exceptional services and unique tours to Iran, Egypt, and Europe. With over 57 years of experience, Cyrus Travel is a trusted source for unforgettable travel experiences.

Jauntee is a premier travel agency located at 7825 Fay Avenue in San Diego, California. With a commitment to providing unforgettable travel experiences, Jauntee offers a wide range of services including personalized trip planning, guided tours, and luxury accommodations. Whether you're looking to explore exotic destinations or embark on a relaxing getaway, Jauntee's team of experienced travel experts are dedicated to creating the perfect itinerary tailored to your preferences. Contact Jauntee today to start planning your dream vacation.

La Jolla Couples Retreat is a luxurious getaway destination located at 7351 Eads Avenue in San Diego, California. As a unique blend of a real estate agency and travel agency, we specialize in providing couples with the perfect romantic escape. Our stunning properties offer breathtaking ocean views, private beach access, and top-notch amenities to ensure a relaxing and unforgettable experience. Whether you're celebrating a special occasion or simply looking to reconnect with your partner, La Jolla Couples Retreat is the ideal destination for a romantic retreat in sunny California.

Grand Amazon Tours is a lodging and travel agency located at 12707 High Bluff Drive, San Diego, California, United States. They offer privately guided, all-inclusive Amazon Rainforest tours in Peru. Their experienced guides provide personalized tours with accommodations in private river view bungalows, complete with hammocks and free WiFi. The lodge is located near Iquitos, Peru, in a pristine, biodiverse area with various wildlife species, including monkeys, sloths, pink dolphins, giant river otters, and more. All meals, transportation, excursions, and a ride on the Amazon River are included in the tour packages. The lodge is the most upstream on the Yanayacu river, ensuring a peaceful and immersive jungle experience. The founders of Grand Amazon Tours are scientists who are passionate about nature conservation and wildlife protection. By staying at the lodge, guests directly contribute to conservation efforts and support local communities.

Andy Travel & Tours is a premier travel agency located at 7710 Balboa Avenue in San Diego, California. With a team of experienced travel experts, we specialize in creating customized travel experiences for our clients. Whether you are looking for a relaxing beach getaway, an adventurous trek through the mountains, or a cultural exploration of a new city, we can help make your travel dreams a reality. From booking flights and accommodations to arranging tours and activities, Andy Travel & Tours is your one-stop shop for all your travel needs. Contact us today to start planning your next unforgettable journey.

Compass Travel Services is a premier travel agency located in San Diego, California. Our experienced team of travel experts is dedicated to providing personalized service and creating unforgettable travel experiences for our clients. Whether you're planning a family vacation, a romantic getaway, or a business trip, we are here to assist you every step of the way. From booking flights and accommodations to arranging tours and activities, we strive to make your travel dreams a reality. Visit us at 8799 Balboa Avenue and let us help you navigate the world with ease.

Connie Lemmon Travel is a reputable travel agency located at 11037 Scripps Ranch Boulevard in San Diego, California. With years of experience in the industry, they specialize in providing personalized travel services to meet the unique needs and preferences of their clients. Whether you are looking to book a family vacation, romantic getaway, or business trip, their team of knowledgeable travel experts is dedicated to helping you plan the perfect itinerary. From booking flights and accommodations to arranging tours and activities, Connie Lemmon Travel is committed to ensuring a seamless and unforgettable travel experience for every client. Visit their office or contact them today to start planning your next adventure.

Kdp Network Inc is a reputable travel agency located in San Diego, California. With a prime location at 11251 Rancho Carmel Drive, this agency offers a wide range of travel services to help clients plan their dream vacations. From booking flights and accommodations to organizing tours and activities, Kdp Network Inc is committed to providing top-notch customer service and ensuring a seamless travel experience for their clients. Whether you're looking for a relaxing beach getaway, an adventurous outdoor expedition, or a cultural exploration, this travel agency has the expertise and resources to make your travel dreams a reality. Contact Kdp Network Inc today to start planning your next unforgettable journey.

eClub USA is a premier travel agency located in the vibrant city of San Diego, California. Our experienced team of travel experts is dedicated to providing personalized service and creating unforgettable travel experiences for our clients. From booking flights and accommodations to arranging tours and activities, we handle every aspect of your trip with care and attention to detail. Whether you're planning a family vacation, romantic getaway, or business trip, eClub USA is here to make your travel dreams a reality. Visit us at 2535 Kettner Boulevard and let us help you explore the world!

Surf & Stay is a premier travel agency located at 707 Pacific Beach Drive in the beautiful city of San Diego, California. Specializing in surf vacations, we offer a unique and unforgettable experience for those looking to catch waves and relax by the beach. Our expert team is dedicated to providing top-notch accommodations, surf lessons, and local recommendations to ensure a seamless and enjoyable trip. Whether you're a seasoned surfer or a beginner looking to try something new, Surf & Stay is the perfect destination for your next adventure. Come join us and make memories that will last a lifetime!

Couch for You is a cozy and welcoming lodging institution located at 1278 1/2 Essex Street in San Diego, California. Our comfortable couches provide the perfect place for travelers to rest and relax during their stay in this vibrant city. Whether you're looking for a budget-friendly option or just a unique experience, Couch for You offers a convenient and affordable accommodation option. Our friendly staff is dedicated to ensuring that your stay is comfortable and enjoyable. Book your stay with us today and experience the comfort of Couch for You.

Aolani Catamaran Sailing is a luxury yacht rental located at 1380 Harbor Island Drive in San Diego, California. With 17 years of experience, this family-owned and operated business offers top-notch catamaran sailing adventures for a variety of occasions. Whether you're interested in a corporate event, day cruise, birthday party, wedding, whale watching excursion, or any other special event, Aolani Catamaran Sailing has you covered. Their 58-foot catamaran can comfortably accommodate up to 48 passengers, making it the perfect choice for intimate gatherings or larger celebrations. The professional Captain and Crew ensure a seamless and safe sailing experience, while the fully stocked premium spirits bar and catering options from local restaurants add an extra touch of luxury. With Coast Guard certification to sail in the open ocean, Aolani Catamaran Sailing offers a wide range of possibilities for custom yacht charters, including day trips, sunset cruises, overnight excursions to Catalina Island, and wildlife watching adventures. The spacious hospitality suite is ideal for corporate events and team building activities, allowing guests to relax and enjoy the stunning views while the crew takes care of the rest. Whether you're looking for a unique way to celebrate a special occasion or simply want to enjoy a day on the water, Aolani Catamaran Sailing is the perfect choice for an unforgettable experience. Contact them today to book your next adventure!

BCS Villas is a premier travel agency located at 2468 Historic Decatur Road in San Diego, California. Our agency specializes in providing luxurious and exclusive villa rentals for travelers looking for a unique and unforgettable vacation experience. With a wide selection of stunning villas in various destinations around the world, BCS Villas offers personalized service and attention to detail to ensure that each client's stay is truly exceptional. Whether you are seeking a beachfront retreat, a mountain escape, or a city oasis, BCS Villas has the perfect accommodation to suit your needs. Contact us today to start planning your dream vacation.