TOP 30 Best Restaurants in Lancaster, South Carolina

South 200 Drive In is a charming food institution located at 1547 Great Falls Road in Lancaster, South Carolina. This classic drive-in restaurant offers a nostalgic dining experience for patrons looking to enjoy delicious comfort food in a retro setting. With a menu featuring classic American favorites like burgers, fries, and milkshakes, South 200 Drive In is a popular spot for families, friends, and anyone craving a taste of the past. Come and experience the old-school charm and tasty treats at South 200 Drive In today!

Tottos Mexican Restaurant is a vibrant and authentic dining establishment located at 126 Elm Street in Lancaster, South Carolina. Offering a wide range of traditional Mexican dishes, Tottos is known for its flavorful and freshly prepared meals that capture the essence of Mexican cuisine. The restaurant's warm and inviting atmosphere makes it the perfect spot for a casual meal with friends or a special celebration with loved ones. With friendly staff and excellent service, Tottos Mexican Restaurant is a must-visit destination for anyone craving delicious Mexican fare in the heart of Lancaster.

The Wagon Wheel Restaurant is a charming dining establishment located at 5724 Lancaster Highway in Fort Lawn, South Carolina. Known for its warm and welcoming atmosphere, this family-friendly restaurant offers a wide range of delicious American cuisine. From hearty burgers and steaks to fresh salads and seafood dishes, there is something on the menu to satisfy every palate. Guests can enjoy their meal in the cozy dining room or opt for outdoor seating on the patio. With friendly service and a relaxed ambiance, the Wagon Wheel Restaurant is the perfect spot for a casual meal with friends or family.

The Wheel-In Restaurant is a beloved dining establishment located at 1751 Pageland Highway in Lancaster, South Carolina. Known for its delicious food and welcoming atmosphere, this restaurant is a popular choice for locals and visitors alike. With a diverse menu featuring a variety of classic American dishes, the Wheel-In Restaurant offers something for everyone. Whether you're craving a juicy burger, crispy fries, or a refreshing milkshake, you're sure to find something to satisfy your appetite at this charming eatery. Come experience the friendly service and mouthwatering meals that have made the Wheel-In Restaurant a staple in the community for years.

Leigh-Anne's Restaurant is a cozy cafe and restaurant located at 200 North Catawba Street in Lancaster, South Carolina. Known for its delicious food and welcoming atmosphere, this institution offers a variety of dishes to satisfy any craving. Whether you're in the mood for a hearty breakfast, a light lunch, or a decadent dinner, Leigh-Anne's has something for everyone. With friendly staff and a charming ambiance, it's the perfect spot to enjoy a meal with family and friends. Visit Leigh-Anne's Restaurant for a delightful dining experience in the heart of Lancaster.

Anne's Restaurant is a charming eatery located at 2194 Pageland Highway in Lancaster, South Carolina. Known for its delicious and hearty meals, this cozy restaurant offers a wide range of delectable dishes to satisfy any palate. Whether you're craving classic American comfort food or looking to try something new, Anne's Restaurant has something for everyone. Come and enjoy a delicious meal in a warm and inviting atmosphere at Anne's Restaurant.

Grinder's Restaurant is a cozy and welcoming eatery located at 208 North Park Drive in Lancaster, South Carolina. Known for its delicious food and friendly service, Grinder's offers a diverse menu with something for everyone. From mouthwatering burgers and sandwiches to fresh salads and hearty entrees, there is no shortage of options to satisfy your cravings. Whether you're looking for a quick bite to eat or a leisurely meal with friends and family, Grinder's Restaurant is the perfect spot to enjoy a tasty meal in a relaxed atmosphere. Come visit us today and see why we're a favorite dining destination in the area.

521 BBQ & Grill in Lancaster, South Carolina is a must-visit for all BBQ lovers. Located at 123 South Main Street, this restaurant offers a wide variety of delicious BBQ dishes including brisket, chicken, chops, ribs, smoked sausage, and wings. Their signature BBQ is made from choice Boston Butts, hand-rubbed with their special seasonings, and hickory smoked for 14 hours every night. At 521 BBQ & Grill, you can enjoy fresh and original BBQ that was prepared the night before in their wood-burning smoker. In addition to their mouthwatering BBQ, they also offer burgers, sandwiches, salads, bowls, and more. Don't forget to try their yummy sides and desserts!

Jo Mars Family Restaurant is a cozy and welcoming eatery located on the bustling Lancaster Bypass East in Lancaster, South Carolina. Known for their delicious and hearty home-cooked meals, this restaurant is a favorite among locals and visitors alike. From mouthwatering burgers and fries to savory pasta dishes and fresh salads, there is something on the menu to satisfy every craving. The friendly staff and charming atmosphere make Jo Mars Family Restaurant the perfect spot for a casual meal with loved ones. Come and experience the warm hospitality and tasty food that keeps customers coming back for more.

Japan Restaurant is a popular dining establishment located at 1160 South Carolina 9 in Lancaster, South Carolina. This authentic Japanese restaurant offers a wide variety of traditional dishes such as sushi, sashimi, ramen, and bento boxes. The cozy atmosphere and friendly staff make it the perfect place to enjoy a delicious meal with friends and family. Whether you're craving fresh seafood or flavorful noodles, Japan Restaurant has something for everyone to enjoy. Come and experience the taste of Japan right here in South Carolina.

Sonic Drive-In is a popular fast food restaurant located at 1501 South Carolina 9 Bypass in Lancaster, South Carolina. Known for their delicious burgers, hot dogs, and signature drinks, Sonic Drive-In offers a unique dining experience with their carhop service and retro-inspired decor. Customers can enjoy their meal in the comfort of their car or at the outdoor patio seating area. With a wide variety of menu options and speedy service, Sonic Drive-In is a favorite spot for families and individuals looking for a quick and tasty meal.

Super 8 by Wyndham Lancaster is a comfortable and affordable lodging option located in Lancaster, South Carolina. Conveniently situated at 1201 Highway 9 Bypass West, this hotel offers a range of amenities including free breakfast, complimentary Wi-Fi, and a seasonal outdoor pool. The rooms are spacious and well-appointed, providing guests with a relaxing environment during their stay. Whether you are visiting for business or leisure, Super 8 by Wyndham Lancaster is a great choice for your accommodation needs in the area.

Smokin' Rail is a popular restaurant located at 1712 Steel Hill Road in Lancaster, South Carolina. This cozy eatery is known for its delicious smoked meats and hearty Southern dishes. The welcoming atmosphere and friendly staff make it a favorite spot for locals and visitors alike. Whether you're craving BBQ ribs, pulled pork, or a juicy burger, Smokin' Rail has something to satisfy every appetite. Come on in and enjoy a tasty meal in a relaxed setting at Smokin' Rail.

Southern Comfort Resort & Spa llc is a luxurious retreat nestled in the heart of Lancaster, South Carolina. Our resort offers a peaceful and serene environment, perfect for relaxation and rejuvenation. With top-notch amenities and world-class services, guests can unwind and pamper themselves in our spa, indulge in delicious cuisine at our on-site restaurant, and enjoy the breathtaking views of the surrounding landscape. Whether you are looking for a romantic getaway, a family vacation, or a solo escape, Southern Comfort Resort & Spa llc is the perfect destination for a memorable and unforgettable experience.

Señor Bigotes is a cozy and inviting restaurant located at 1358 Flat Creek Road in Lancaster, South Carolina. This charming establishment offers a delicious menu of traditional Mexican cuisine, featuring flavorful dishes such as tacos, burritos, enchiladas, and more. With its warm and welcoming atmosphere, Señor Bigotes is the perfect place to enjoy a satisfying meal with friends and family. Whether you're craving spicy salsa or a refreshing margarita, this restaurant is sure to please your taste buds. Come visit Señor Bigotes for a taste of authentic Mexican flavors in the heart of South Carolina.

The Grandma's House Cafe is a charming restaurant located at 2704 Flat Creek Road in Lancaster, South Carolina. This cozy establishment offers a warm and inviting atmosphere reminiscent of a grandmother's kitchen. Serving up delicious home-cooked meals and baked goods, The Grandma's House Cafe is the perfect spot to enjoy a comforting meal with family and friends. With friendly service and a menu full of traditional favorites, this cafe is a must-visit for anyone looking for a taste of home.

Jo Jo's Backyard BBQ is a cozy restaurant located at 2009 North Rocky River Road in Lancaster, South Carolina. Known for serving the finest Carolina-style BBQ, JoJo's offers a warm and welcoming atmosphere for families to enjoy delicious BBQ dishes. The hickory-smoked BBQ is cooked to perfection, making it tender and finger-lickin' good. The menu includes pulled pork, ribs, BBQ chicken, and a variety of mouthwatering side dishes and homemade desserts. Whether you're passing by on Interstate 77 or in the area, JoJo's is a must-visit for BBQ lovers. With rave reviews and ratings, this restaurant is a favorite among locals and travelers alike. Don't forget to try their signature mustard sauce and vinegar pepper sauce, and remember to bring cash as they do not accept cards. Overall, Jo Jo's Backyard BBQ is a true gem for anyone craving authentic Carolina BBQ.

La Piñata Tacos & Tequila is a vibrant and authentic Mexican restaurant located at 4471 Pageland Highway in Lancaster, South Carolina. Step inside and experience a lively atmosphere filled with the delicious aromas of freshly made tacos and the smooth taste of premium tequila. Our menu features a wide variety of traditional Mexican dishes made with fresh ingredients and bold flavors. Whether you're craving street-style tacos, sizzling fajitas, or refreshing margaritas, La Piñata Tacos & Tequila has something for everyone. Come join us for a fiesta of flavors and let us transport you to Mexico with every bite.

Cafe 200 is a charming restaurant located at 1691 Great Falls Road in Lancaster, South Carolina. Known for its cozy atmosphere and delicious food, Cafe 200 is a popular spot for locals and visitors alike. The menu features a variety of dishes, including sandwiches, salads, and comfort food favorites. Whether you're stopping in for a quick bite or a leisurely meal, Cafe 200 is the perfect place to relax and enjoy good food in a welcoming environment.

Grab&Go Sandwich n Boba Tea is a popular food destination located at 1307 Charlotte Highway in Lancaster, South Carolina. This cozy restaurant offers a variety of delicious and freshly made sandwiches and refreshing boba teas for customers on-the-go. Whether you're looking for a quick bite to eat or a tasty drink to quench your thirst, Grab&Go Sandwich n Boba Tea has something for everyone. Stop by and experience their unique and flavorful menu in a relaxed and casual setting.

Buford Little General Store is a charming convenience store located at 1897 North Rocky River Road in Lancaster, South Carolina. This beloved institution offers a wide variety of food, snacks, drinks, and household items for local residents and travelers passing through. In addition to its convenient store offerings, Buford Little General Store also features a small restaurant serving up delicious meals and hearty Southern comfort food. Whether you're in need of a quick bite to eat, a refreshing drink, or some last-minute essentials, Buford Little General Store has you covered. Swing by and experience the warm hospitality and friendly service that this local gem is known for.

Chick-fil-A is a popular fast food restaurant located at 901 Highway 9 Bypass West in Lancaster, South Carolina. Known for their delicious chicken sandwiches and waffle fries, Chick-fil-A offers a variety of menu options for breakfast, lunch, and dinner. The restaurant is known for its friendly service and commitment to providing high-quality food in a clean and welcoming environment. Chick-fil-A is a favorite among locals and visitors alike for its tasty meals and convenient location.

Mully's is a cozy and welcoming restaurant located at 695 Lancaster Bypass East in Lancaster, South Carolina. Known for its delicious and hearty comfort food, Mully's offers a diverse menu featuring a variety of dishes to satisfy all tastes. Whether you're in the mood for a juicy burger, a crispy salad, or a comforting bowl of soup, Mully's has something for everyone. With friendly service and a laid-back atmosphere, Mully's is the perfect spot to enjoy a satisfying meal with family and friends. Come visit us and experience the delicious flavors of Mully's for yourself!

Punkys On Main is a vibrant and eclectic restaurant located at 306 South Main Street in Lancaster, South Carolina. Known for its unique and creative menu, Punkys On Main offers a variety of delicious dishes that cater to all tastes and preferences. From classic comfort foods to innovative fusion cuisine, there is something for everyone at this popular eatery. The casual and welcoming atmosphere makes it the perfect spot for a relaxed meal with friends or family. Whether you're looking for a quick bite to eat or a leisurely dining experience, Punkys On Main is sure to delight your taste buds and leave you wanting more.

Frog's Bar & Grill is a cozy and inviting establishment located at 2063 Great Falls Highway in Lancaster, South Carolina. This popular spot offers a wide range of delicious food and drinks, making it the perfect place to unwind and enjoy a meal with friends or family. Whether you're looking for a casual night out or a lively atmosphere to watch the game, Frog's Bar & Grill has something for everyone. With friendly staff, great service, and a welcoming environment, this restaurant is sure to become your new favorite hangout spot.

Johnny Boys Diner is a charming restaurant located at 500 East Arch Street in Lancaster, South Carolina. Known for its delicious comfort food and friendly service, this diner is a favorite spot for locals and visitors alike. The cozy atmosphere and retro decor make it the perfect place to enjoy a hearty meal with family and friends. Whether you're craving a classic burger and fries or a homestyle plate of meatloaf and mashed potatoes, Johnny Boys Diner has something for everyone. Stop by for a taste of Southern hospitality and a satisfying dining experience.

521 Country Cooking is a charming restaurant located in Lancaster, South Carolina. Known for its delicious home-style meals and friendly service, this cozy establishment offers a wide variety of comforting dishes that will satisfy any craving. From traditional Southern favorites like fried chicken and mashed potatoes to mouthwatering desserts like peach cobbler, 521 Country Cooking is sure to please even the pickiest of eaters. Whether you're stopping in for a quick bite or looking to enjoy a leisurely meal with friends and family, this inviting restaurant is the perfect spot to enjoy a taste of true Southern hospitality.

Hwy 55 Burgers Shakes & Fries is a popular restaurant located in Lancaster, South Carolina. Known for its delicious burgers, thick milkshakes, and crispy fries, this institution offers a classic American dining experience. Whether you're craving a juicy burger, a refreshing shake, or some perfectly seasoned fries, Hwy 55 has something for everyone. Stop by 683 South Carolina 9 Bypass to enjoy a tasty meal in a friendly and welcoming atmosphere.

La Chalupa is a family-friendly Mexican restaurant located at 775 Lancaster Bypass East in Lancaster, South Carolina. Since 1996, we have been serving delicious Mexican cuisine to the Lancaster community. Our menu includes appetizers, combination dinners, fajitas, nachos, vegetarian options, and a lunch menu. We also have a full-service bar with daily margarita specials. Our restaurant features a new private dining room that can accommodate up to 100 guests, perfect for private parties or events. We also offer a Mexican buffet with American cuisine options for lunch and dinner, as well as a lunch buffet seven days a week and a dinner buffet on Sundays.

ATM is a cozy and inviting restaurant located at 1667 Memorial Park Road in Lancaster, South Carolina, United States. Known for its delicious food and friendly service, ATM offers a diverse menu featuring a variety of flavorful dishes to satisfy any craving. Whether you're in the mood for a hearty meal or a light snack, ATM has something for everyone. Stop by and enjoy a delicious meal in a warm and welcoming atmosphere.