TOP 30 Best Business hotel in South Carolina

The Shepherd Hotel, located at 110 Sloan Street in Clemson, South Carolina, offers a warm boutique lodging experience in the heart of downtown. Each room is carefully designed for comfort, every event is set against stunning views, and our team is dedicated to providing heartfelt hospitality to every guest. Owned in partnership with Dabo Swinney, the Clemson University Head Football Coach, The Shepherd Hotel is committed to serving guests, the team, and the community. Our sophisticated guest rooms feature curated amenities, custom furnishings, and original art, creating a feeling of homecoming for every visitor.

Located at 1224 Taylor Street in Columbia, South Carolina, Hotel Trundle is a unique lodging experience that combines kindness, comfort, and creativity. Situated in the heart of the Main Street District, this 41-room hotel is housed within three historic buildings that have been beautifully combined into one. The eclectic, 20s-era Art Deco style of the hotel creates a welcoming and charming atmosphere for guests. Each room and suite at Hotel Trundle features design and furnishings from local artists and craftspeople, offering a personal touch that reflects the vibrant culture of Columbia. Step outside the hotel and explore the Main Street District, where you can discover farmers markets, pop-up events, and local Columbia favorites.

Located in the heart of Greenville, South Carolina, the Cambria Hotel offers a modern and comfortable lodging experience. Situated at 135 Carolina Point Parkway, this hotel provides easy access to popular attractions, shopping centers, and dining options. The stylish rooms are equipped with all the amenities needed for a relaxing stay, including plush bedding, flat-screen TVs, and free Wi-Fi. Guests can enjoy a delicious meal at the on-site restaurant or grab a drink at the bar. The hotel also features a fitness center, outdoor pool, and meeting rooms for business travelers. Whether you're visiting for business or leisure, the Cambria Hotel Greenville is the perfect choice for your stay in this vibrant city.

The Inn at I'On, Ascend Hotel Collection is a charming lodging located at 148 Civitas Street in Mount Pleasant, South Carolina. Nestled in the picturesque I'On community, this boutique hotel offers a unique and tranquil retreat for guests. The Inn features elegant rooms and suites, each thoughtfully designed for comfort and relaxation. Guests can enjoy modern amenities, such as complimentary breakfast, free Wi-Fi, and a fitness center. The hotel's convenient location provides easy access to nearby attractions, including historic downtown Charleston and the beautiful beaches of the South Carolina coast. Whether you are visiting for business or pleasure, the Inn at I'On offers a peaceful and memorable stay in the heart of the Lowcountry.

Holiday Inn Express & Suites Latta, an IHG Hotel, is a comfortable and convenient lodging option located at 2513 Cattle Farm Road in Latta, South Carolina, United States. This modern hotel offers a range of amenities including complimentary breakfast, free high-speed internet access, a fitness center, and an outdoor pool. The hotel is perfect for both business and leisure travelers looking for a relaxing stay in a peaceful setting. With friendly staff and clean, spacious rooms, Holiday Inn Express & Suites Latta is the ideal choice for your next visit to the area.

Holiday Inn Express & Suites Aiken, an IHG Hotel, is a charming lodging establishment located at 2897 Whiskey Road in Aiken, South Carolina, United States. This modern hotel offers comfortable accommodations and excellent amenities for both business and leisure travelers. Guests can enjoy a complimentary hot breakfast, a fitness center, a seasonal outdoor pool, and free high-speed internet access. The hotel's convenient location provides easy access to local attractions, shopping, and dining options. Whether you are visiting Aiken for work or pleasure, Holiday Inn Express & Suites Aiken is the perfect choice for your stay.

Located in the heart of downtown Columbia in the vibrant Vista district, Cambria Hotel Columbia Downtown offers modern and stylish lodging for both business and leisure travelers. The hotel features contemporary design, spacious rooms, and top-notch amenities such as a fitness center, rooftop pool, and on-site restaurant and bar. With its convenient location near popular attractions, shopping, and dining options, Cambria Hotel Columbia Downtown is the perfect choice for a comfortable and enjoyable stay in South Carolina's capital city.

AC Hotel by Marriott Spartanburg is a sleek and modern lodging option located at 225 West Main Street in the heart of Spartanburg, South Carolina. This stylish hotel offers contemporary design, comfortable accommodations, and top-notch amenities for both business and leisure travelers. Guests can enjoy a European-inspired breakfast, a fitness center, a rooftop bar with stunning city views, and convenient access to downtown attractions. Whether visiting for work or pleasure, AC Hotel by Marriott Spartanburg provides a sophisticated and comfortable stay in a prime location.

Staybridge Suites Charleston-Ashley Phosphate, an IHG Hotel, is a cozy and inviting lodging option located in North Charleston, South Carolina. Situated at 7329 Mazyck Road, this hotel offers comfortable and spacious suites perfect for both short and extended stays. Guests can enjoy amenities such as a fully equipped kitchen in each suite, complimentary breakfast, a fitness center, and a relaxing outdoor pool. The hotel's convenient location provides easy access to popular attractions, shopping centers, and dining options in the area. Whether you are traveling for business or leisure, Staybridge Suites Charleston-Ashley Phosphate is the perfect home away from home.

Located in the charming town of Mount Pleasant, South Carolina, the Cambria Hotel offers a luxurious and comfortable stay for guests visiting the Charleston area. Situated just a short drive from the historic city of Charleston, this modern hotel boasts stylish rooms, top-notch amenities, and friendly service. Whether you're in town for business or leisure, the Cambria Hotel Mount Pleasant - Charleston is the perfect choice for a relaxing and enjoyable stay.

Holiday Inn Express North Augusta - SC, an IHG Hotel, is a comfortable and convenient lodging option located at 138 Stephens Farm Lane in North Augusta, South Carolina, United States. This hotel offers modern amenities and spacious rooms, perfect for both business and leisure travelers. Guests can enjoy a complimentary breakfast, free Wi-Fi, a fitness center, and a refreshing outdoor pool. The hotel's friendly staff is always ready to assist with any needs or requests, making your stay a pleasant and memorable experience. Whether you are visiting for work or relaxation, Holiday Inn Express North Augusta - SC is the ideal choice for your stay in the area.

Staybridge Suites Rock Hill is a cozy and comfortable lodging option conveniently located at 493 Galleria Boulevard in Rock Hill, South Carolina. As an IHG Hotel, guests can expect top-notch amenities and exceptional service during their stay. The hotel offers spacious suites equipped with fully-equipped kitchens, free Wi-Fi, and flat-screen TVs. Guests can also enjoy complimentary breakfast, a fitness center, outdoor pool, and a business center. Whether traveling for business or leisure, Staybridge Suites Rock Hill provides a welcoming and relaxing environment for all guests.

Holiday Inn Express & Suites Greenville S - Piedmont, an IHG Hotel, is a modern and comfortable lodging option located in Piedmont, South Carolina. Situated at 3004 South Carolina 153, this hotel offers convenient access to nearby attractions such as downtown Greenville, Falls Park on the Reedy, and the Greenville Zoo. Guests can enjoy a range of amenities during their stay, including a complimentary breakfast buffet, a fitness center, and an outdoor pool. The hotel also offers free Wi-Fi, on-site parking, and a business center for those traveling for work.

Holiday Inn Express & Suites Greenville SE - Simpsonville is a modern and comfortable lodging option located at 642 Fairview Road in Simpsonville, South Carolina. As an IHG Hotel, guests can expect top-notch service and amenities during their stay. The hotel offers spacious and well-appointed rooms and suites, along with a complimentary breakfast buffet to start the day off right. Guests can also enjoy the indoor pool, fitness center, and business center during their stay. With its convenient location and excellent facilities, Holiday Inn Express & Suites Greenville SE - Simpsonville is the perfect choice for both business and leisure travelers visiting the area.

The Hampton Inn Anderson/Alliance Business Park is a comfortable and convenient lodging option located at 411 Alliance Parkway in Anderson, South Carolina. Situated in the heart of the Alliance Business Park, this hotel offers easy access to local businesses, shopping, and dining options. Guests can enjoy a range of amenities including a complimentary hot breakfast, free Wi-Fi, a fitness center, and an outdoor pool. Whether traveling for business or leisure, the Hampton Inn Anderson/Alliance Business Park provides a welcoming and relaxing stay for all guests.

Holiday Inn Express & Suites Charleston-North, an IHG Hotel, is a comfortable and convenient lodging option located at 2435 Elms Center Road in North Charleston, South Carolina, United States. This hotel offers a range of amenities, including a complimentary breakfast buffet, free Wi-Fi, a fitness center, and an outdoor pool. The rooms are spacious and well-appointed, providing a relaxing environment for guests to unwind after a day of exploring the nearby attractions. Whether you are traveling for business or leisure, Holiday Inn Express & Suites Charleston-North is the perfect choice for your stay in the Charleston area.

Holiday Inn Express & Suites Charleston NE Mt Pleasant Us17, an IHG Hotel, is a comfortable and convenient lodging option located in Mount Pleasant, South Carolina. Situated at 1104 Stockade Lane, this hotel offers modern amenities and spacious accommodations for guests looking to explore the charming town of Mount Pleasant or nearby Charleston. With a complimentary breakfast buffet, fitness center, and outdoor pool, guests can enjoy a relaxing stay while being just a short drive away from popular attractions such as Patriots Point Naval & Maritime Museum and the historic district of Charleston. Whether traveling for business or leisure, Holiday Inn Express & Suites Charleston NE Mt Pleasant Us17 is the perfect choice for a memorable stay in the Lowcountry.

Holiday Inn Express & Suites Greenville - Taylors, an IHG Hotel, is a comfortable and convenient lodging option located in Greenville, South Carolina. Situated at 2025 Wade Hampton Boulevard, this hotel offers modern amenities and spacious accommodations for both business and leisure travelers. Guests can enjoy complimentary breakfast, free Wi-Fi, a fitness center, and a refreshing outdoor pool. The hotel is conveniently located near popular attractions, restaurants, and shopping destinations in the area. Whether you are visiting for work or pleasure, Holiday Inn Express & Suites Greenville - Taylors provides a welcoming and relaxing stay for all guests.

Cambria Hotel Summerville - Charleston is a luxurious lodging option located at 405 Sigma Drive in Summerville, South Carolina, United States. This modern and stylish hotel offers comfortable accommodations with upscale amenities and top-notch service. Guests can enjoy spacious rooms, a fitness center, an outdoor pool, a restaurant, and a bar. The hotel is conveniently located near popular attractions in Charleston and provides easy access to shopping, dining, and entertainment options. Whether you are visiting for business or leisure, Cambria Hotel Summerville - Charleston is the perfect choice for a relaxing and enjoyable stay.

Holiday Inn Express Lexington is a modern and comfortable hotel located at 325 West Main Street in Lexington, South Carolina. As part of the IHG Hotel group, guests can expect high-quality accommodations and excellent service during their stay. The hotel offers spacious rooms with modern amenities, a complimentary breakfast buffet, a fitness center, and a business center. Conveniently located near popular attractions and dining options, Holiday Inn Express Lexington is the perfect choice for both leisure and business travelers visiting the area.

Holiday Inn Columbia - Downtown, an IHG Hotel, is a modern and comfortable lodging option located at 1233 Washington Street in the heart of Columbia, South Carolina. With its convenient location, guests can easily explore the city's attractions, restaurants, and shops. The hotel offers spacious rooms, on-site dining options, a fitness center, and meeting facilities, making it a perfect choice for both leisure and business travelers. Experience excellent service and hospitality at Holiday Inn Columbia - Downtown.

Located at 425 Meeting Street in the charming city of Charleston, South Carolina, The Limited Hotel offers a luxurious and comfortable lodging experience. Our hotel is perfect for travelers looking for a peaceful and relaxing stay, with spacious rooms and top-notch amenities. Whether you are visiting for business or pleasure, The Limited Hotel is the perfect choice for your accommodation needs. Book your stay with us today and experience the ultimate in hospitality and comfort.

Church Street Inn, Ascend Hotel Collection is a charming lodging establishment located at 177 Church Street in the historic city of Charleston, South Carolina, United States. This boutique hotel offers a unique and cozy atmosphere for guests looking to immerse themselves in the rich history and culture of Charleston. The hotel features beautifully decorated rooms with modern amenities, a welcoming lobby area, and friendly staff who are dedicated to providing top-notch service. Guests can enjoy the convenience of being centrally located near popular attractions, shopping, and dining options. Whether you are visiting for business or pleasure, Church Street Inn, Ascend Hotel Collection is the perfect choice for a memorable stay in Charleston.

Holiday Inn Express & Suites Fort Mill, an IHG Hotel, is a modern and comfortable lodging option located at 1655 Carolina Place in Fort Mill, South Carolina. This hotel offers a convenient location near popular attractions, shopping centers, and dining options. Guests can enjoy spacious and well-appointed rooms and suites, as well as amenities such as a complimentary breakfast buffet, fitness center, and outdoor pool. Whether visiting for business or leisure, Holiday Inn Express & Suites Fort Mill provides a welcoming and relaxing stay for all guests.

The Cambria Hotel Fort Mill is a stylish and modern lodging option located at 340 Amistead Avenue in Fort Mill, South Carolina. This hotel offers comfortable and spacious rooms, as well as a range of amenities including a fitness center, outdoor pool, and on-site dining options. Conveniently situated near popular attractions and businesses, the Cambria Hotel Fort Mill is the perfect choice for both leisure and business travelers looking for a comfortable and convenient stay in the area.

Holiday Inn Express & Suites Richburg, an IHG Hotel, is a modern and comfortable lodging option located at 3190 Commerce Drive in Richburg, South Carolina, United States. This hotel offers a range of amenities and services to ensure a pleasant stay for guests, including free breakfast, a fitness center, an outdoor pool, and complimentary high-speed internet access. The rooms are spacious and well-appointed, featuring plush bedding, a flat-screen TV, a work desk, and a coffee maker. Whether you are traveling for business or leisure, Holiday Inn Express & Suites Richburg is a convenient and welcoming choice for your stay in the area.

Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd is a modern and comfortable lodging option located in the heart of Greenville, South Carolina. Situated at 1036 Woodruff Road, this hotel offers convenient access to the I-85 highway and is just a short drive away from popular attractions such as Falls Park on the Reedy and the Greenville Zoo. Guests can enjoy a range of amenities during their stay, including spacious rooms and suites, complimentary breakfast, a fitness center, and an outdoor pool. The hotel's central location makes it an ideal choice for both business and leisure travelers looking to explore all that Greenville has to offer.

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 is a modern and comfortable lodging option located in Florence, South Carolina. Situated conveniently off of Highway 327, this IHG hotel offers a range of amenities and services to ensure a pleasant stay for guests. The spacious rooms and suites are tastefully decorated and equipped with all the necessary facilities for a relaxing stay. Guests can enjoy complimentary breakfast, access to the fitness center, and a refreshing indoor pool. The hotel's convenient location provides easy access to nearby attractions and dining options. Whether traveling for business or leisure, Holiday Inn Express & Suites Florence I-95 @ Hwy 327 is a great choice for a comfortable and enjoyable stay in South Carolina.

Crowne Plaza North Augusta, an IHG Hotel, is a luxurious lodging option located at 1060 Center Street in North Augusta, South Carolina, United States. This upscale hotel offers modern amenities and stylish accommodations for both business and leisure travelers. Guests can enjoy spacious rooms, on-site dining options, a fitness center, and a rooftop bar with stunning views of the city. With its convenient location near popular attractions and business districts, Crowne Plaza North Augusta is the perfect choice for those looking for a comfortable and convenient stay in the area.

Staybridge Suites Greenville I-85 Woodruff Road, an IHG Hotel, is a modern and comfortable lodging option located in Greenville, South Carolina. Situated at 31 Market Point Drive, this hotel offers convenient access to the I-85 highway and is in close proximity to various shopping and dining options. The hotel features spacious suites with fully equipped kitchens, free Wi-Fi, and a complimentary breakfast buffet. Guests can also enjoy amenities such as a fitness center, outdoor pool, and a business center. Whether traveling for business or leisure, Staybridge Suites Greenville I-85 Woodruff Road provides a welcoming and convenient stay for all guests.