TOP 30 Relaxing weekend getaway in Hannibal, Missouri

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Main Street Bed & Breakfast is a charming lodging establishment located at 201 North Main Street in the historic town of Hannibal, Missouri. This cozy bed and breakfast offers comfortable accommodations for guests looking to explore the sights and attractions of Mark Twain's hometown. The beautifully decorated rooms provide a relaxing retreat, while the welcoming atmosphere and friendly staff ensure a memorable stay. Conveniently situated on Main Street, guests can easily access the shops, restaurants, and landmarks that make Hannibal a popular destination. Whether you're visiting for a weekend getaway or a longer stay, Main Street Bed & Breakfast is the perfect home base for your Missouri adventure.

Reagan's Queen Anne Bed and Breakfast is a charming lodging establishment located at 313 North 5th Street in Hannibal, Missouri, United States. This historic bed and breakfast offers cozy rooms and a warm, inviting atmosphere for guests to relax and unwind. The beautifully restored Queen Anne-style architecture adds to the charm of this quaint inn. Guests can enjoy a delicious homemade breakfast each morning and explore the nearby attractions in the charming town of Hannibal. Whether you are visiting for a romantic getaway or a weekend escape, Reagan's Queen Anne Bed and Breakfast is the perfect place to stay.

Fifth Street Mansion B&B is a charming bed and breakfast located at 213 South 5th Street in the historic town of Hannibal, Missouri, United States. This elegant institution offers cozy and comfortable accommodations for guests looking to experience the beauty and charm of the area. The B&B features beautifully decorated rooms, delicious homemade breakfasts, and personalized service to ensure a memorable stay. Whether you are visiting Hannibal for a weekend getaway or exploring the nearby attractions such as Mark Twain's Boyhood Home and Museum, Fifth Street Mansion B&B is the perfect choice for a relaxing stay.

Welcome to Dubach Inn - Bed and Breakfast, located at 221 North 5th Street in Hannibal, Missouri, United States. Our charming inn offers cozy and comfortable accommodations for travelers looking for a home away from home. Each room is tastefully decorated and equipped with modern amenities to ensure a pleasant stay. Guests can enjoy a delicious homemade breakfast each morning, served in our elegant dining room. Conveniently located near local attractions and dining options, Dubach Inn is the perfect choice for your next stay in Hannibal. Book your room today and experience the warmth and hospitality of our bed and breakfast.

Sixth Street Guest Haus is a charming lodging facility located at 407 North 6th Street in Hannibal, Missouri, United States. Situated in a historic building, this guest house offers comfortable and cozy accommodations for travelers looking to experience the quaint charm of Hannibal. With its convenient location near popular attractions such as Mark Twain Boyhood Home and Museum, guests can easily explore the town's rich history and culture. Whether you're visiting for a weekend getaway or an extended stay, Sixth Street Guest Haus provides a welcoming atmosphere and personalized service to ensure a memorable experience for all guests.

The Quarry House is a charming lodging establishment located at 511 Birch Street in Hannibal, Missouri. This cozy retreat offers comfortable accommodations for guests looking to relax and unwind in a peaceful setting. The Quarry House is known for its welcoming atmosphere, friendly staff, and convenient location near popular attractions in Hannibal. Whether you're visiting for a weekend getaway or an extended stay, The Quarry House is the perfect choice for your lodging needs. Experience the warmth and hospitality of this hidden gem in the heart of Missouri.

Jackpot Junction is a vibrant and exciting bar and night club located at 223 Bird Street in Hannibal, Missouri. This popular establishment offers a lively atmosphere, great music, and delicious drinks to enjoy with friends or to meet new people. With a prime location in the heart of Hannibal, Jackpot Junction is the perfect spot to unwind after a long day or to kick off a night of fun and entertainment. Whether you're looking to dance the night away or simply relax with a drink, Jackpot Junction has something for everyone. Come join us for a memorable night out in Hannibal!

Bluffview is a picturesque campground, lodging, and park located in Center, Missouri, United States. Situated near Mark Twain Lake, this institution offers a serene setting for boating and fishing enthusiasts. Visitors can unwind on the Salt River and immerse themselves in the history of the area, imagining the adventures of Mark Twain's iconic characters like Tom Sawyer and Huck Finn. The day-use recreation area features amenities such as a boat ramp, playground, and picnic shelters, making it a perfect spot for a family outing or a relaxing weekend getaway. Surrounded by tree-covered hills, the scenic landscape of Mark Twain Lake and the Salt River provides a tranquil escape from the hustle and bustle of everyday life.

Welcome to Bayview Campers Park Nestled just 3 miles north of historic Hannibal, Missouri, Bayview Campers Park offers a serene escape in the heart of nature. Situated at 9430 Missouri 168, Palmyra, our campground spans 23 picturesque acres and features three beautiful lakes, making it an ideal destination for outdoor enthusiasts and families alike.

Welcome to The Meadow Campground & Coffee House, your serene escape nestled along the historic Salt River in New London, Missouri. Located at 15301 U.S. 61, our charming retreat offers a unique camping experience surrounded by the natural beauty of Missouri's lush deciduous trees. Whether you're seeking a rustic adventure or a cozy getaway, The Meadow provides the perfect backdrop for making lasting memories with family and friends. Immerse yourself in the tranquility of our handcrafted, Amish-built cabins, complete with modern amenities such as heating, cooling, TV, and a DVD player. For those who prefer a more traditional camping experience, our RV sites offer full hookups, while our primitive tent sites are perfectly positioned along the river's edge for a true back-to-nature experience.

Welcome to Lighthouse Inn & Suites, your home away from home in the heart of Hannibal, Missouri. Conveniently located at 612 Mark Twain Avenue, our charming lodging offers the perfect blend of comfort, convenience, and classic hospitality. Whether you're visiting for business or leisure, you'll find our well-appointed rooms and suites are designed to provide a relaxing and enjoyable stay. At Lighthouse Inn & Suites, we pride ourselves on offering exceptional service and a warm, welcoming atmosphere. Our accommodations feature modern amenities, including complimentary Wi-Fi, flat-screen TVs, and plush bedding to ensure a restful night's sleep. Start your day with our delicious continental breakfast before exploring the historic charm of Hannibal, the hometown of renowned author Mark Twain.