The 30 Best Southern cuisine restaurants in Clarksdale, Mississippi

Ramon's Restaurant is a cozy and welcoming dining establishment located in Clarksdale, Mississippi. Situated at 300 North Edwards Avenue, this popular restaurant offers a diverse menu of delicious dishes that are sure to satisfy any craving. Whether you're in the mood for traditional Southern comfort food or something a bit more exotic, Ramon's has something for everyone. With its friendly staff and inviting atmosphere, Ramon's Restaurant is the perfect spot to enjoy a tasty meal with friends and family. Come visit us today and experience the mouthwatering flavors that make Ramon's a local favorite.

Bobbie's Diner is a charming restaurant located at 1208 North State Street in Clarksdale, Mississippi. This beloved diner is a local favorite, known for its delicious comfort food and friendly atmosphere. Whether you're craving a classic burger and fries or a hearty plate of southern-style fried chicken, Bobbie's Diner has something for everyone. Stop by for a taste of traditional American cuisine and enjoy a meal in a cozy setting that feels like home.

Ramon's is a charming restaurant located at 535 Oakhurst Avenue in Clarksdale, Mississippi. Known for its delicious food and welcoming atmosphere, Ramon's offers a diverse menu of mouthwatering dishes served in a cozy setting. Whether you're craving classic Southern comfort food or international cuisine, Ramon's has something for everyone. Come dine with us and experience the flavors of Clarksdale at Ramon's.

Rest Haven is a cozy and welcoming restaurant located at 419 South State Street in Clarksdale, Mississippi. Known for its delicious comfort food and friendly atmosphere, this institution is a popular choice for locals and visitors alike. With a menu featuring classic Southern dishes and homemade desserts, Rest Haven is the perfect place to enjoy a satisfying meal in a charming setting. Whether you're looking for a hearty breakfast, a tasty lunch, or a satisfying dinner, Rest Haven has something for everyone to enjoy. Come dine with us and experience true Southern hospitality at its finest.

Lil Sistas is a cozy and welcoming restaurant located at 282 Sunflower Avenue in Clarksdale, Mississippi. Specializing in delicious comfort food and southern cuisine, Lil Sistas offers a variety of mouthwatering dishes that will leave you wanting more. With a warm and inviting atmosphere, this institution is the perfect place to enjoy a meal with friends and family. Come visit Lil Sistas for a taste of true southern hospitality and flavors that will satisfy your cravings.

Kenoy's is a beloved food institution located at 4125 Friars Point Road in Clarksdale, Mississippi. Known for its delicious and authentic Southern cuisine, this restaurant offers a variety of dishes that are sure to satisfy any craving. From mouth-watering barbecue to hearty soul food classics, Kenoy's is a must-visit for anyone looking for a taste of true Southern hospitality. Whether you're a local or just passing through, be sure to stop by Kenoy's for a meal that will leave you coming back for more.

Abe's Bar-B-Q is a beloved institution located at 616 North State Street in Clarksdale, Mississippi. Known for its mouthwatering barbecue dishes, this restaurant offers a cozy and inviting atmosphere where guests can enjoy delicious smoked meats and savory sides. Whether you're craving ribs, brisket, or pulled pork, Abe's Bar-B-Q has something for everyone. Come experience the flavors of the South at this iconic eatery in the heart of Mississippi.

Pearl 88 is a charming restaurant located at 1410 North State Street in Clarksdale, Mississippi. Known for its delicious and authentic cuisine, Pearl 88 offers a diverse menu of food options that are sure to satisfy any craving. Whether you're in the mood for traditional Southern comfort food or international dishes, Pearl 88 has something for everyone. The cozy atmosphere and friendly staff make it a perfect spot for a casual meal or a special occasion. Come dine at Pearl 88 and experience the flavors of Mississippi in every bite.

Crossroad’s Catfish is a renowned restaurant located at 906 North State Street in Clarksdale, Mississippi. Specializing in serving delicious catfish dishes, this institution offers a cozy and inviting atmosphere for guests to enjoy a satisfying meal. Whether you prefer your catfish fried, grilled, or blackened, Crossroad’s Catfish has something for everyone. With friendly service and a menu full of Southern comfort food favorites, this restaurant is a must-visit for anyone looking to experience authentic Mississippi cuisine.

Hicks Tamales & BBQ Shop is a beloved institution located at 305 South State Street in Clarksdale, Mississippi. This unique establishment offers a delicious combination of traditional tamales and mouthwatering BBQ dishes. Whether you're in the mood for a hearty meal or looking to satisfy your cravings for authentic Southern cuisine, Hicks Tamales & BBQ Shop is the perfect place to visit. Their friendly staff and cozy atmosphere make it a favorite spot for locals and visitors alike. Don't miss out on a chance to experience the flavors of Mississippi at this charming restaurant and store.

The Compound at the Crossroads is a charming restaurant located at 1108 Desoto Avenue in Clarksdale, Mississippi. Situated at the crossroads of tradition and innovation, this institution offers a unique dining experience that blends classic Southern flavors with modern culinary techniques. Guests can expect a warm and inviting atmosphere, attentive service, and a menu that showcases the best of Mississippi cuisine. Whether you're craving comfort food favorites or looking to explore new culinary creations, The Compound at the Crossroads is sure to delight your taste buds and leave you wanting more.