TOP 30 Modern hotel accommodations in Missouri

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Located in the heart of downtown St. Louis, the 21c Museum Hotel St. Louis is a unique lodging experience that combines a boutique hotel with a contemporary art museum. Housed in a historic YMCA building, the hotel features 173 rooms, a restaurant, cafe, and a full-service wellness center. With over 14,000 square feet of exhibition and event space, guests can immerse themselves in contemporary art around every corner. The hotel offers a variety of room options, from twin beds to spacious suites, each with modern amenities and unique historic features. Guests can also enjoy dining credits, free parking, and special packages during their stay. The hotel is committed to fostering innovation and community engagement through its programming and events, making it a vibrant cultural hub in the city. Whether you're visiting for a weekend getaway or a special event, the 21c Museum Hotel St. Louis offers a truly one-of-a-kind experience.

Located at 1515 Wyandotte Street in Kansas City, Missouri, the Loews Kansas City Hotel offers spacious accommodations and festive cuisine for a memorable stay this holiday season. Book one of our well-appointed suites for extra room, comfort, and amenities, all with Loews' genuine and attentive service included. With 800 guestrooms, a lobby bar, on-site restaurant, grab & go coffee shop, indoor lap pool, and 60,000 square feet of meeting and event space, the hotel is conveniently located near key attractions such as the Kansas City Power & Light District, T-Mobile Center, and the Kauffman Center for the Performing Arts. Take advantage of state-of-the-art services and amenities including an indoor saltwater lap pool and 2,600 square foot fitness center. Whether you're planning a wedding, meeting, or simply looking for a special getaway, Loews Kansas City Hotel has something for everyone. Welcome to the Loews family and enjoy special offers from Loews Hotels & Co. during your stay.

Holiday Inn Express & Suites St. Louis - Chesterfield, an IHG Hotel, is a modern and comfortable lodging option located in Chesterfield, Missouri. Situated at 11 Arnage Boulevard, this hotel offers a convenient location for both business and leisure travelers. The hotel features spacious and well-appointed rooms and suites, perfect for a relaxing stay. Guests can enjoy amenities such as complimentary breakfast, free Wi-Fi, a fitness center, and an indoor pool. Whether you're visiting for work or pleasure, Holiday Inn Express & Suites St. Louis - Chesterfield is a great choice for your stay in the St. Louis area.

SureStay Plus Hotel by Best Western St. Louis Airport is a cozy and convenient lodging option located at 11380 Natural Bridge Road in Bridgeton, Missouri. Just minutes away from St. Louis Lambert International Airport, this hotel offers comfortable accommodations for travelers looking for a relaxing stay. The hotel features modern amenities, including free Wi-Fi, a fitness center, a complimentary hot breakfast, and a seasonal outdoor pool. Whether you are visiting for business or pleasure, SureStay Plus Hotel by Best Western St. Louis Airport provides a welcoming atmosphere and excellent service to make your stay enjoyable.

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel, is a modern and stylish lodging option located at 1100 Lodora Drive in Wentzville, Missouri, United States. This hotel offers comfortable and spacious rooms and suites, perfect for both business and leisure travelers. Guests can enjoy amenities such as complimentary breakfast, a fitness center, an indoor pool, and free Wi-Fi throughout the property. The hotel's convenient location provides easy access to popular attractions in the St. Louis area. Whether you're visiting for work or pleasure, Holiday Inn Express & Suites Wentzville St Louis West is the perfect choice for your stay.

Holiday Inn Express & Suites St Charles, an IHG Hotel, is a comfortable and convenient lodging option located at 3098 Elm Point Industrial Drive in Saint Charles, Missouri, United States. The hotel offers a range of amenities including complimentary breakfast, free high-speed internet access, a fitness center, and an indoor pool. The modern and well-appointed rooms provide a relaxing stay for both business and leisure travelers. With its convenient location near attractions such as the historic Main Street and the St. Charles Convention Center, Holiday Inn Express & Suites St Charles is an ideal choice for those looking to explore the area.

Holiday Inn Express St. Louis - Central West End, an IHG Hotel, is a modern and comfortable lodging option located in the vibrant city of St. Louis, Missouri. Situated at 4630 Lindell Boulevard, this hotel offers convenient access to popular attractions such as Forest Park, the St. Louis Zoo, and the iconic Gateway Arch. Guests can enjoy a complimentary breakfast, free Wi-Fi, and access to a fitness center during their stay. With friendly staff and cozy accommodations, Holiday Inn Express is the perfect choice for travelers looking for a relaxing and enjoyable stay in the heart of St. Louis.

Holiday Inn Express & Suites St. Louis South - I-55, an IHG Hotel, is a comfortable and convenient lodging option located at 4250 Midamerica Lane in St. Louis, Missouri, United States. This modern hotel offers a range of amenities including complimentary breakfast, a fitness center, and an indoor pool. The spacious guest rooms and suites are equipped with free Wi-Fi, flat-screen TVs, and comfortable bedding to ensure a relaxing stay. Whether you are traveling for business or leisure, Holiday Inn Express & Suites St. Louis South - I-55 provides a welcoming atmosphere and excellent service for all guests.

Candlewood Suites St. Louis - St. Charles, an IHG Hotel is a comfortable and modern lodging establishment located at 1800 Zumbehl Road in Saint Charles, Missouri. This hotel offers spacious and well-equipped suites for guests looking for a home away from home during their stay in the St. Louis area. Amenities include fully equipped kitchens, free Wi-Fi, a fitness center, laundry facilities, and a convenience store. The hotel is conveniently located near attractions such as the Historic Main Street, Ameristar Casino, and the St. Charles Convention Center. Whether you are visiting for business or pleasure, Candlewood Suites St. Louis - St. Charles provides a convenient and comfortable stay for all travelers.

The Renaissance St. Louis Airport Hotel is a premier lodging destination located at 9801 Natural Bridge Road in St. Louis, Missouri, United States. This elegant hotel offers luxurious accommodations and top-notch amenities for travelers looking for a comfortable stay near the airport. With a sophisticated design and modern facilities, guests can enjoy a relaxing and convenient experience during their visit. Whether you're traveling for business or leisure, the Renaissance St. Louis Airport Hotel is the perfect choice for your stay in St. Louis.

Holiday Inn Express & Suites St. Louis Airport, an IHG Hotel, is a modern and comfortable lodging option conveniently located at 10000 Natural Bridge Road in St. Louis, Missouri. This hotel offers a range of amenities including spacious rooms, a fitness center, complimentary breakfast, and free Wi-Fi. Perfect for both business and leisure travelers, the Holiday Inn Express & Suites is just a short drive from the airport and other popular attractions in the area. Experience exceptional service and a relaxing stay at this well-appointed hotel.

The Best Western Plus St. Louis Airport Hotel is a top-rated lodging option conveniently located at 4576 Woodson Road in St. Louis, Missouri. This modern hotel offers comfortable accommodations and a range of amenities for both business and leisure travelers. Guests can enjoy a complimentary breakfast, free Wi-Fi, a fitness center, and an outdoor pool. The hotel's prime location near the airport makes it a convenient choice for travelers flying in and out of St. Louis. Whether you're visiting for business or pleasure, the Best Western Plus St. Louis Airport Hotel provides a welcoming and comfortable stay for all guests.

St. Louis Airport Hotel is a comfortable and convenient lodging option located at 9600 Natural Bridge Road in St. Louis, Missouri. This hotel is perfect for travelers looking for a place to stay near the airport, as it offers easy access to the terminals. The hotel features modern amenities, spacious rooms, and friendly staff to ensure a pleasant stay for guests. Whether you are in town for business or pleasure, St. Louis Airport Hotel is a great choice for your accommodation needs.

Drury Plaza Hotel St. Louis St. Charles is a luxurious lodging establishment located at 380 Mulholland Drive in Saint Charles, Missouri, United States. This elegant hotel offers comfortable and stylish accommodations for guests visiting the area. With modern amenities, excellent service, and a convenient location, Drury Plaza Hotel is the perfect choice for both business and leisure travelers. Enjoy a relaxing stay in spacious rooms, take a dip in the indoor pool, or dine at the on-site restaurant. Experience the best of St. Charles hospitality at Drury Plaza Hotel.

Best Western St. Louis Airport North Hotel & Suites is a top-rated lodging facility located at 323 Taylor Road in Hazelwood, Missouri. This modern hotel offers comfortable accommodations and excellent amenities for both business and leisure travelers. Guests can enjoy spacious rooms and suites, a fitness center, complimentary breakfast, and a convenient location near St. Louis Lambert International Airport. Whether you are visiting for work or pleasure, Best Western St. Louis Airport North Hotel & Suites is the perfect choice for your stay in the St. Louis area.

Staybridge Suites St Louis - Westport, an IHG Hotel, is a charming lodging establishment located at 25 Progress Parkway in Maryland Heights, Missouri. This hotel offers comfortable and spacious suites equipped with modern amenities, perfect for both short and extended stays. Guests can enjoy complimentary breakfast, a fitness center, an outdoor pool, and a business center. Conveniently located near Westport Plaza, guests can easily access shopping, dining, and entertainment options. With friendly staff and a welcoming atmosphere, Staybridge Suites St Louis - Westport is the ideal choice for travelers looking for a relaxing and enjoyable stay in the St Louis area.

The Aviator Hotel & Suites South I-55, BW Signature Collection is a premier lodging destination located at 6921 South Lindbergh Boulevard in St. Louis, Missouri, United States. This stylish and modern hotel offers comfortable accommodations and top-notch amenities for both business and leisure travelers. Guests can enjoy spacious rooms, a fitness center, a business center, and a complimentary breakfast. The hotel's convenient location near the I-55 highway makes it easy to explore all that St. Louis has to offer. Whether you're visiting for work or pleasure, the Aviator Hotel & Suites is the perfect choice for your stay in the Gateway City.

The Pennywell St. Louis Downtown, a Hilton Hotel, is a luxurious lodging option located at 400 Olive Street in the heart of St. Louis, Missouri. This elegant hotel offers modern amenities and stylish accommodations for both business and leisure travelers. Guests can enjoy a prime location near popular attractions, upscale dining options, and vibrant nightlife. With impeccable service and top-notch facilities, The Pennywell St. Louis Downtown is the perfect choice for a memorable stay in St. Louis.

The AC Hotel by Marriott St. Louis Central West End is a modern and stylish lodging option located at 215 York Avenue in the vibrant city of St. Louis, Missouri. This hotel offers luxurious accommodations and top-notch amenities for both leisure and business travelers. Situated in the trendy Central West End neighborhood, guests can enjoy easy access to shopping, dining, and entertainment options. With its sleek design, comfortable rooms, and exceptional service, the AC Hotel by Marriott is the perfect choice for those looking for a chic and convenient stay in St. Louis.

Hotel St. Louis Downtown City Center MO is a premier lodging establishment located at 400 South 14th Street in the heart of St. Louis, Missouri. This modern hotel offers luxurious accommodations and top-notch amenities to ensure a comfortable and enjoyable stay for guests. Conveniently situated near popular attractions, dining, and entertainment options, Hotel St. Louis Downtown City Center MO is the perfect choice for travelers looking to experience all that the city has to offer. With impeccable service and a prime location, this hotel is ideal for both business and leisure travelers seeking a memorable stay in St. Louis.

Hotel Ignacio is a boutique hotel located in the heart of St. Louis, Missouri, at 3411 Olive Street. This unique lodging institution offers a blend of modern amenities and artistic flair, making it a one-of-a-kind destination for travelers. With stylishly decorated rooms, a vibrant atmosphere, and top-notch service, Hotel Ignacio provides guests with a comfortable and memorable stay. Whether you're in town for business or pleasure, this hotel is the perfect choice for those looking for a distinctive and enjoyable experience in St. Louis.

The Last Hotel STL, located at 1501 Washington Avenue in St. Louis, Missouri, is a unique institution offering a combination of bar, food, lodging, and restaurant services. By booking directly, guests can enjoy a free 1 level room upgrade and early access to The Last Rooftop, based on availability. The institution also offers a Guest Book cash rewards program. While the restaurant, Ultima Cucina, is currently under construction due to a recent fire, guests can look forward to its reopening soon. The hotel boasts award-winning rooms with a 4-star rating and offers secure garage parking starting at $40. Guests can also enjoy the Last Rooftop Pool, an exclusive amenity for guests of The Last Hotel.

Hotel Indigo St. Louis - Downtown, an IHG Hotel, is a stylish and modern lodging option located in the heart of downtown St. Louis, Missouri. Situated at 501 Olive Street, this hotel offers a unique and vibrant atmosphere that reflects the local culture and heritage of the city. With comfortable and well-appointed rooms, guests can enjoy a relaxing stay while being just steps away from popular attractions such as the Gateway Arch, Busch Stadium, and the St. Louis Riverfront. Whether you are visiting for business or leisure, Hotel Indigo St. Louis - Downtown provides a welcoming and convenient accommodation option for your stay in the "Gateway to the West".

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, is a luxurious lodging establishment located at 421 North 8th Street in the heart of St. Louis, Missouri. This historic hotel offers elegant accommodations, modern amenities, and exceptional service to ensure a comfortable stay for all guests. With its prime location near popular attractions such as the Gateway Arch and Busch Stadium, Magnolia Hotel St. Louis is the perfect choice for travelers looking to experience the best that the city has to offer. Whether visiting for business or pleasure, guests can relax in style and sophistication at this upscale hotel.

The Drury Plaza Hotel St. Louis At The Arch is a luxurious lodging institution located at 2 South 4th Street in the heart of St. Louis, Missouri, United States. This stunning hotel offers modern amenities, comfortable accommodations, and breathtaking views of the iconic Gateway Arch. Guests can enjoy a complimentary hot breakfast, evening snacks, and access to the indoor pool and fitness center. Whether visiting for business or leisure, the Drury Plaza Hotel provides a convenient and stylish stay in the vibrant city of St. Louis.

Economy Hotel St. Louis is a cozy and affordable lodging option located at 4545 Woodson Road in St. Louis, Missouri. Our hotel offers comfortable rooms with modern amenities, friendly staff, and convenient access to local attractions and businesses. Whether you are traveling for business or pleasure, Economy Hotel St. Louis provides a welcoming and budget-friendly accommodation option for your stay in the heart of the United States.

The Drury Plaza Hotel Cape Girardeau Conference Center is a premier lodging destination located at 3351 Percy Drive in Cape Girardeau, Missouri, United States. This modern and stylish hotel offers comfortable accommodations, top-notch amenities, and a convenient location for both business and leisure travelers. With a dedicated conference center on-site, this institution is the perfect choice for hosting meetings, events, and gatherings of all sizes. Guests can enjoy a relaxing stay, delicious dining options, and exceptional service at the Drury Plaza Hotel Cape Girardeau Conference Center.

The Marquette Hotel is a charming lodging establishment located at 399-301 North Fountain Street in Cape Girardeau, Missouri. This historic hotel offers a unique and comfortable stay for guests visiting the area. With its convenient location and cozy accommodations, the Marquette Hotel is the perfect choice for travelers looking for a memorable experience in the heart of Cape Girardeau. Enjoy modern amenities and friendly service at this inviting hotel in the United States.

Holiday Inn Express & Suites St. Joseph, an IHG Hotel, is a welcoming lodging establishment located at 3600 North Village Drive in Saint Joseph, Missouri, United States. This hotel offers comfortable accommodations and modern amenities for both leisure and business travelers. Guests can enjoy a complimentary breakfast, free high-speed internet access, a fitness center, and an indoor pool. The hotel's convenient location provides easy access to local attractions, shopping, and dining options. Whether you are visiting for work or pleasure, Holiday Inn Express & Suites St. Joseph is the perfect place to relax and unwind during your stay in the area.

Holiday Inn Express & Suites Kansas City Airport, an IHG Hotel, is a modern and comfortable lodging option conveniently located at 9550 Northwest Polo Drive in Kansas City, Missouri, United States. This hotel is perfect for both leisure and business travelers, offering a range of amenities such as free breakfast, a fitness center, an indoor pool, and a business center. The rooms are stylishly decorated and equipped with modern conveniences to ensure a pleasant stay. With its close proximity to Kansas City Airport, guests can easily access the hotel and explore all that the city has to offer. Whether you're visiting for a quick stopover or an extended stay, Holiday Inn Express & Suites Kansas City Airport provides a welcoming and convenient accommodation option.