TOP 30 American grille specials in Murphysboro, Illinois

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Mi Patio Mexican Grill is a vibrant and authentic Mexican restaurant located in Murphysboro, Illinois. Situated at 13693 Illinois 149, this establishment offers a warm and inviting atmosphere where guests can enjoy delicious Mexican cuisine and refreshing drinks. Whether you're in the mood for traditional tacos, sizzling fajitas, or flavorful margaritas, Mi Patio Mexican Grill has something for everyone. Come experience a taste of Mexico right in the heart of Illinois at this bustling bar and restaurant.

St. Nicholas Brewing Co. MDH is a cozy and inviting restaurant located at 665 North Airport Road in Murphysboro, Illinois. Known for its delicious food and craft beers, this institution offers a unique dining experience for locals and visitors alike. The menu features a variety of dishes made with fresh, locally sourced ingredients, as well as a rotating selection of handcrafted beers brewed on site. Whether you're looking for a casual meal with friends or a special night out, St. Nicholas Brewing Co. MDH is the perfect place to enjoy great food and drinks in a laid-back atmosphere.