The 30 Best Hearty sandwiches in San Francisco, California

Mel's Drive-In is a classic American diner located on Lombard Street in San Francisco, California. Known for its retro 1950s decor and delicious comfort food, Mel's Drive-In offers a wide variety of options for breakfast, lunch, and dinner. Whether you're craving a juicy burger, a stack of fluffy pancakes, or a hearty milkshake, Mel's Drive-In has something for everyone. Pull up to one of the iconic red booths and enjoy a taste of nostalgia at this beloved institution.

Hidden Spot in South San Francisco is a cozy and inviting bar and restaurant located on Grand Avenue. Tucked away from the hustle and bustle of the city, this hidden gem offers a relaxed atmosphere where guests can enjoy delicious food and drinks. The menu features a variety of tasty dishes, from savory appetizers to hearty entrees. Whether you're looking for a place to unwind after work or catch up with friends over a meal, Hidden Spot is the perfect spot to escape and enjoy good company. With its warm ambiance and friendly staff, it's no wonder this spot is a favorite among locals and visitors alike. Come discover this hidden treasure in South San Francisco and make it your new go-to spot for a night out.

Darby Dan's Sandwiches is a popular food establishment located at 733 Airport Boulevard in South San Francisco, California. This restaurant and store specializes in delicious, freshly made sandwiches that are perfect for a quick and satisfying meal on the go. With a variety of options to choose from, including classic deli sandwiches, gourmet paninis, and specialty wraps, Darby Dan's has something to satisfy every craving. Whether you're looking for a hearty lunch or a tasty snack, this institution is sure to leave you feeling satisfied and coming back for more.

Big Apple Pizza N Grill is a popular restaurant located at 127 Eddy Street in San Francisco, California. Known for their delicious grilled chicken and red onions topped with hot buffalo sauce, as well as a variety of other mouth-watering dishes, this pizzeria has become a favorite among locals. From classic pizzas with fresh toppings to hearty salads and sandwiches, there is something for everyone at Big Apple Pizza N Grill. In addition to their tasty menu offerings, the restaurant also offers convenient curbside pickup and regular deals on food. Support local businesses and enjoy a taste of the best pizza in San Francisco at Big Apple Pizza N Grill.

Duboce Park Cafe is a cozy and inviting cafe located in the heart of San Francisco, just steps away from the beautiful Duboce Park. Our menu offers a variety of delicious options, from our carefully sourced Park Coffee and hearty breakfast dishes to fresh salads, sandwiches, smoothies, and juices made with locally sourced ingredients. Whether you're looking for a quick bite on the go or a leisurely meal with your family and furry friends, Duboce Park Cafe has something for everyone. Our commitment to quality shines through in every dish we serve, with ingredients that are always fresh and flavors that are always satisfying. Come experience the charm of our cafe and taste the difference for yourself.

Anton's Pizza & Deli is a beloved institution located in the heart of San Francisco, California. Known for its delicious pizzas and gourmet deli sandwiches, this restaurant offers a wide variety of options for both dine-in and delivery. Whether you're craving a classic pepperoni pizza or a hearty pastrami sandwich, Anton's has something for everyone. With its convenient location on Folsom Street, Anton's is the perfect spot to grab a quick bite to eat or enjoy a leisurely meal with friends and family. Come experience the mouthwatering flavors and friendly service that make Anton's Pizza & Deli a must-visit destination in San Francisco.

Dolores Park Cafe is a charming cafe located at 501 Dolores Street in San Francisco, California. This cafe offers a variety of delicious food options, from hearty breakfasts to healthy salads and sandwiches, as well as fresh smoothies and juices made with locally sourced ingredients. Their coffee is sourced responsibly from different regions around the world and roasted in-house on San Francisco’s first emission-free coffee roaster. Customers rave about the great taste and aroma of their Park Coffee.

L's Caffe is a charming bakery, cafe, and restaurant located in the heart of San Francisco, California. Situated at 2871 24th Street, this cozy spot offers a wide range of delicious food and beverages to satisfy your cravings. Whether you're in the mood for freshly baked pastries, gourmet coffee, savory sandwiches, or hearty meals, L's Caffe has something for everyone. With its welcoming atmosphere and friendly staff, this institution is the perfect place to relax and enjoy a tasty meal or treat. Visit L's Caffe today and experience a true taste of San Francisco!

Beanstalk Cafe is a cozy and inviting cafe located at 4555 California Street in the bustling city of San Francisco, California. Known for its delicious food and welcoming atmosphere, this cafe is a popular spot for locals and tourists alike. Whether you're looking for a quick bite to eat or a leisurely meal with friends, Beanstalk Cafe has something for everyone. From freshly brewed coffee and pastries to hearty sandwiches and salads, you'll find a wide variety of options to satisfy your cravings. Come in and relax with a hot cup of coffee or enjoy a tasty meal in this charming cafe in the heart of San Francisco.

Mellis Cafe is a charming bakery and cafe located at 154 Ellis Street in the heart of San Francisco, California. Offering a cozy and inviting atmosphere, Mellis Cafe is the perfect spot to enjoy a delicious meal or treat. From freshly baked pastries to hearty sandwiches and salads, there is something for everyone to enjoy. With friendly staff and a welcoming ambiance, Mellis Cafe is a must-visit destination for food lovers in San Francisco.

Lou's Cafe is a charming eatery located at 5017 Geary Boulevard in the vibrant city of San Francisco, California. This cozy cafe offers a wide range of delicious food options, from freshly brewed coffee to mouth-watering pastries and hearty sandwiches. Whether you're looking for a quick bite to eat or a relaxing place to enjoy a meal with friends, Lou's Cafe is the perfect spot. With its welcoming atmosphere and friendly staff, this cafe is a must-visit destination for anyone looking for a tasty meal in the heart of San Francisco.

Mercury Cafe is a charming cafe located at 201 Octavia Street in the heart of San Francisco, California. This cozy establishment offers a diverse menu of delicious food and drinks, perfect for a quick bite or a leisurely meal. The cafe has a relaxed and welcoming atmosphere, making it a popular spot for locals and visitors alike. Whether you're in the mood for a cup of coffee, a hearty sandwich, or a fresh salad, Mercury Cafe has something to satisfy your cravings. Come and enjoy a tasty meal in a laid-back setting at Mercury Cafe.

Moffitt Cafe at UCSF Medical Center is a bustling institution located at 505 Parnassus Avenue in San Francisco, California. This cafe offers a variety of delicious food options for visitors, patients, and staff members. The cafe is open Monday through Friday from 6:30 am to 7:00 pm, and on weekends and holidays from 7:00 am to 3:00 pm. Additionally, Moffitt Cafe Express, located on the second floor of Moffitt Hospital, is open Monday through Friday from 5:30 am to midnight, and on weekends and holidays from 6:00 am to 8:00 pm.

Garden House Cafe is a charming and cozy eatery located in the heart of San Francisco, California. Situated at 3117 Clement Street, this cafe is a popular spot for locals and visitors alike to enjoy delicious food in a relaxed and inviting atmosphere. From freshly brewed coffee and pastries to hearty sandwiches and salads, Garden House Cafe offers a diverse menu to satisfy any craving. Whether you're looking for a quick bite to eat or a leisurely meal with friends, this cafe is the perfect place to unwind and enjoy good food in a beautiful setting.

Sutter Street Cafe is a charming and cozy eatery located at 450 Sutter Street in the heart of San Francisco, California. This bustling cafe offers a wide variety of delicious food options, including freshly brewed coffee, hearty breakfast dishes, gourmet sandwiches, and scrumptious pastries. Whether you're looking for a quick bite to eat on-the-go or a relaxing sit-down meal, Sutter Street Cafe has something for everyone. With convenient meal delivery options available, you can enjoy their tasty fare wherever you are in the city. Come visit Sutter Street Cafe and experience the perfect blend of comfort, convenience, and culinary delight.

Joy's Place is a charming cafe and restaurant located in the heart of San Francisco, California. Situated at 611 Post Street, this cozy establishment offers a delightful array of delicious food and beverages for customers to enjoy. From freshly brewed coffee and decadent pastries to hearty sandwiches and salads, Joy's Place has something for everyone. Additionally, visitors can browse through a selection of unique gifts and souvenirs at the on-site store. Whether you're looking for a quick bite to eat or a leisurely meal with friends, Joy's Place is the perfect destination for a satisfying dining experience in a welcoming atmosphere.

New Lun Ting Cafe is a cozy and inviting eatery located at 670 Jackson Street in the heart of San Francisco's Chinatown. This beloved cafe offers a wide range of delicious Chinese and American dishes, from traditional dim sum to hearty burgers and sandwiches. The warm and friendly atmosphere makes it the perfect spot for a casual meal or a quick snack. Whether you're craving a steaming bowl of noodles or a refreshing cup of tea, New Lun Ting Cafe has something for everyone. Come visit us and experience the flavors of Chinatown in every bite.

Lou's Cafe is a charming eatery located in the heart of San Francisco, California. Situated at 1508 Taraval Street, this cozy cafe offers a warm and inviting atmosphere for guests to enjoy delicious food and beverages. Whether you're in the mood for a hearty breakfast, a light lunch, or a sweet treat, Lou's Cafe has something for everyone. From freshly brewed coffee to decadent pastries, this cafe is the perfect spot to relax and unwind. Come visit Lou's Cafe and experience the taste of San Francisco!

Brothers Cafe, located at 382 Grand Avenue in South San Francisco, California, is a family-owned restaurant founded by first generation Greek-Americans, Kosta and Billy. With a rich history in the restaurant industry, the brothers have carried on their family legacy of serving classic American comfort food in a fast casual setting. Indoor and outdoor dining options are available, and customers can also choose delivery or pickup options. The institution also includes BREW382, offering a selection of beers. Whether you're looking for a hearty meal or a refreshing drink, Brothers Cafe is the perfect spot to enjoy delicious food and friendly service.

Squat & Gobble Café is a charming and cozy eatery located in the heart of San Francisco's West Portal neighborhood. This popular café offers a diverse menu of delicious and fresh food options, ranging from hearty breakfast dishes to savory sandwiches and salads. Whether you're looking for a quick bite to eat or a leisurely meal with friends, Squat & Gobble Café is the perfect spot to satisfy your cravings. With its friendly staff, inviting atmosphere, and convenient location, this café is a beloved destination for locals and visitors alike. Come experience the warm hospitality and mouthwatering cuisine at Squat & Gobble Café, located at 1 West Portal Avenue in San Francisco, California.

Cafe International is a charming café located at 508 Haight Street in the heart of San Francisco, California. Known for its cozy atmosphere and delicious food, this café offers a wide range of menu options for breakfast, lunch, and dinner. Whether you're in the mood for a hearty sandwich, a fresh salad, or a decadent dessert, Cafe International has something for everyone. Stop by for a cup of their specialty coffee or tea, and enjoy a relaxing meal in this bustling neighborhood. With friendly staff and a welcoming ambiance, Cafe International is the perfect spot to unwind and enjoy a tasty meal in San Francisco.

YakiniQ CAFE is a cozy and inviting cafe located at 1640 Post Street in the heart of San Francisco, California. This unique establishment offers a wide range of delicious food options, including freshly brewed coffee, tasty pastries, and hearty sandwiches. In addition to its cafe offerings, YakiniQ CAFE also doubles as a store, selling a variety of gourmet snacks and local products. Whether you're looking for a quick bite to eat or a place to relax with a cup of coffee, YakiniQ CAFE is the perfect spot to satisfy your cravings.

Cafe Encore is a cozy and inviting cafe located in the heart of San Francisco, California. Situated at 488 Post Street, this charming establishment offers a wide range of delicious food and beverages to satisfy your cravings. Whether you're in the mood for a freshly brewed cup of coffee, a hearty sandwich, or a decadent dessert, Cafe Encore has something for everyone. With its warm atmosphere and friendly staff, it's the perfect spot to relax and enjoy a meal with friends or grab a quick bite on the go. Come visit Cafe Encore and experience a delightful dining experience in the bustling city of San Francisco.

All Star Cafe is a cozy and inviting cafe located at 1306 Mission Street in the bustling city of San Francisco, California. This charming establishment offers a wide range of delicious food options, from freshly brewed coffee to mouth-watering pastries and hearty sandwiches. Whether you're looking for a quick bite on your way to work or a relaxing spot to catch up with friends, All Star Cafe has something for everyone. With its warm and welcoming atmosphere, friendly staff, and convenient location, it's no wonder why this cafe is a favorite among locals and visitors alike. Come on in and experience the All Star Cafe difference today!

Angelina's Deli Cafe is a charming eatery located at 6000 California Street in the bustling city of San Francisco, California. This cozy cafe offers a variety of delicious food options for breakfast, lunch, and dinner. From hearty sandwiches and fresh salads to decadent pastries and gourmet coffee, Angelina's Deli Cafe has something to satisfy every craving. The welcoming atmosphere and friendly staff make it the perfect spot to grab a quick bite to eat or enjoy a leisurely meal with friends. Stop by Angelina's Deli Cafe today and experience the true taste of San Francisco.

Morning Due Cafe is a charming eatery located at 3698 17th Street in the heart of San Francisco, California. This cozy cafe is the perfect spot to grab a quick meal or snack on the go, offering a wide range of delicious food options for breakfast, lunch, and dinner. Whether you're in the mood for a freshly brewed cup of coffee, a hearty sandwich, or a mouthwatering dessert, Morning Due Cafe has something for everyone. With its welcoming atmosphere and friendly staff, this cafe is a favorite spot for locals and visitors alike. Stop by and experience the tasty offerings at Morning Due Cafe today!

Located in San Francisco, California, Dolores Park Cafe at SFO Terminal 2 Concourse C is a charming cafe that offers a variety of delicious food options. Start your day off right with a cup of their Park Coffee and a hearty breakfast, or enjoy a healthy salad or sandwich for lunch. Their smoothies and juices are made with fresh, locally sourced ingredients and are perfect for a mid-afternoon pick-me-up. The cafe takes pride in their carefully sourced and responsibly roasted coffee beans, which are roasted in-house on San Francisco's first emission free coffee roaster. Their food is made from scratch with only the finest ingredients, ensuring top quality and flavor in every bite. Customers rave about the tasty vegan options, fresh sandwiches, and overall healthy and delicious food choices at Dolores Park Cafe.

Lucky Ocean Cafe is a charming eatery located at 1501 Ocean Avenue in the heart of San Francisco, California. This cozy cafe offers a delightful menu of delicious food and beverages, perfect for breakfast, lunch, or a quick snack. Whether you're craving a hearty sandwich, a fresh salad, or a decadent dessert, Lucky Ocean Cafe has something for everyone. Come in and enjoy a relaxing meal in a welcoming atmosphere with friendly staff. Experience the taste of the ocean at Lucky Ocean Cafe.

Mr. T Cafe is a cozy and welcoming cafe located at 4689 Mission Street in San Francisco, California. Known for its delicious food and friendly atmosphere, this cafe is a popular spot for locals and visitors alike. Whether you're in the mood for a hearty breakfast, a light lunch, or a tasty snack, Mr. T Cafe has something for everyone. Stop by and enjoy a cup of freshly brewed coffee or tea, along with a selection of freshly baked pastries and sandwiches. With its convenient location and great food, Mr. T Cafe is the perfect place to relax and refuel during your day in San Francisco.

Red Cafe is a cozy and welcoming eatery located at 2894 Mission Street in the vibrant city of San Francisco, California. This charming cafe offers a variety of delicious food options, ranging from freshly brewed coffee and pastries to hearty sandwiches and salads. Whether you're looking for a quick bite to eat or a relaxing meal with friends, Red Cafe is the perfect spot to satisfy your cravings. Come visit us and experience our warm atmosphere and tasty menu offerings for yourself!